San Francisco 49ers vs. Los Angeles Rams - 12/21/19 NFL Pick, Odds, and Prediction

Los Angeles Rams (8-6) at San Francisco 49ers (11-3)

NFL Football: Saturday, December 21, 2019 at 8:15 pm (Levi's Stadium)

The Line: San Francisco 49ers -6.5 -- Over/Under: 46 Click Here for the Latest Odds

Where to Watch: NFL Stream live sports and exclusive originals on ESPN+. Sign up now! Advertisement

The Los Angeles Rams and San Francisco 49ers meet Saturday in week 16 NFL action at Levi's Stadium.

The Los Angeles Rams look for a win after splitting their last 10 games. The Los Angeles Rams have split their last six road games. Jared Goff is completing 63.2 percent of his passes for 3,996 yards, 17 touchdowns and 15 interceptions. Goff has one or less touchdown passes in 11 of his last 19 games. Cooper Kupp and Robert Woods have combined for 1,981 receiving yards and nine touchdowns while Tyler Higbee has 52 receptions. The Los Angeles Rams ground game is averaging 93.9 yards per contest, and Todd Gurley II leads the way with 741 yards and 10 touchdowns. Defensively, Los Angeles is allowing 21.9 points and 336.2 yards per game. Cory Littleton leads the Los Angeles Rams with 124 tackles, Aaron Donald has 11 sacks and John Johnson III has two interceptions.

The San Francisco 49ers look for a win after splitting their last six games. The San Francisco 49ers have won four of their last six home games. Jimmy Garoppolo is completing 69.1 percent of his passes for 3,445 yards, 26 touchdowns and 11 interceptions. Garoppolo has four touchdown passes in three of his last seven games. George Kittle and Deebo Samuel have combined for 1,557 receiving yards and seven touchdowns while Emmanuel Sanders has 30 receptions. The San Francisco 49ers ground game is averaging 147 yards per contest, and Raheem Mostert leads the way with 662 yards and five touchdowns. Defensively, San Francisco is allowing 18.4 points and 269 yards per game. Fred Warner leads the San Francisco 49ers with 104 tackles, Arik Armstead has 10 sacks and Richard Sherman has three interceptions.

See which Cappers are CASHING IN.. Click Here to see the HOTTEST CAPPERS!!!!

The Rams are 7-2 ATS in their last 9 road games, 4-1 ATS in their last 5 vs. NFC and 13-6 ATS in their last 19 games overall. The 49ers are 6-1 ATS in their last 7 Saturday games, 2-7-1 ATS in their last 10 vs. NFC West and 3-1-1 ATS in their last 5 games overall. The under is 7-2 in Rams last 9 games overall. The over is 6-2 in 49ers last 8 games overall. The Rams are 2-6 ATS in their last 8 meetings. The under is 5-1 in the last 6 meetings in San Francisco. 

The Los Angeles Rams are a really confusing team, as one minute they're beating up on the Seahawks to save their season and the next they get dominated by a struggling and bad Cowboys team. It would be nice if the Rams made up their mind and decided if they're a good team or not. The San Francisco 49ers went from being a dominant 8-0 team to losing three of their next six games and seeing a shutdown defense give up 75 points in their last two games. The Rams need this game if they're going to make a run for the playoffs and they have the guys in the trenches to give the 49ers issues up front. I don't like what I've seen from the San Francisco 49ers defensively these last two weeks. Rivalry division game with a lot on the line. I'll take the free touchdown. 

Risk Free Bets, Free Bets and Deposit Bonuses CLICK HERE!!!!

Randy’s Pick Los Angeles Rams +6.5

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

San Francisco 49ers vs Los Angeles Rams NFL Pick and Prediction 12/21/19 Week 16 NFL Betting Tips

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.