Arizona Cardinals at San Francisco 49ers - 11/17/19 NFL Pick, Odds, and Prediction

Arizona Cardinals at San Francisco 49ers - 11/17/19 NFL Pick, Odds, and Prediction Photo by Mark J. Rebilas-USA TODAY Sports

Arizona Cardinals (3-6-1) at San Francisco 49ers (8-1)

NFL Football: Sunday, November 17, 2019 at 4:05 pm (Levi's Stadium)

The Line: San Francisco 49ers -10.5 -- Over/Under: 45

TV: FOX

The Arizona Cardinals and San Francisco 49ers meet Sunday in NFL action at Levi's Stadium.

The Arizona Cardinals could use a win after splitting their last six games. The Arizona Cardinals have lost three of their last five road games. Kyler Murray is completing 63.9 percent of his passes for 2,553 yards, 12 touchdowns and five interceptions. Murray enters this game with 360 career pass attempts. Larry Fitzgerald and Christian Kirk have combined for 1,023 receiving yards and five touchdowns while David Johnson has 31 receptions. The Arizona Cardinals ground game is averaging 116 yards per contest, and Murray leads the way with 351 yards and two touchdowns. Defensively, Arizona is allowing 28.1 points and 412.5 yards per game. Jordan Hicks leads the Arizona Cardinals with 98 tackles, Chandler Jones has 11.5 sacks and Patrick Peterson has one interception.

The San Francisco 49ers look for a bounce back performance after losing their first game last week to Seattle in overtime. The San Francisco 49ers have won three of their last four home games. Jimmy Garoppolo is completing 67.6 percent of his passes for 2,054 yards, 14 touchdowns and eight interceptions. Garoppolo has 18 touchdown passes in his last 11 games. George Kittle and Deebo Samuel have combined for 880 receiving yards and three touchdowns while Kendrick Bourne has 15 receptions. The San Francisco 49ers ground game is averaging 161.8 yards per contest, and Matt Breida leads the way with 542 yards and one touchdown. Defensively, San Francisco is allowing 14.3 points and 251.6 yards per game. Fred Warner leads the San Francisco 49ers with 58 tackles, Nick Bosa has seven sacks and Richard Sherman has three interceptions.

The Cardinals are 5-2 ATS in their last 7 vs. NFC West, 4-1 ATS in their last 5 vs. NFC and 5-1 ATS in their last 6 games overall. The 49ers are 1-4 ATS in their last 5 games in November, 2-7 ATS in their last 9 vs. NFC West and 5-13 ATS in their last 18 vs. NFC. The Cardinals are 4-1 ATS in their last 5 meetings in San Francisco and 4-0 ATS in their last 4 meetings. The over is 5-1 in 49ers last 6 vs. NFC West. The over is 5-1 in Cardinals last 6 games on grass.

The Arizona Cardinals are 5-3 ATS in their last eight games as a double-digit underdog. The San Francisco 49ers are 2-6 ATS in their last eight games as a double-digit favorite. The Arizona Cardinals continue to compete and play hard, as five of their last six games have resulted in either a victory or a loss by three points. The San Francisco 49ers are coming off a physical Monday night loss that needed overtime to be decided, so they not only have less time to prepare, but there could be some wear and tear that shows up in this one. Either way, the Cardinals show up to play each week and fight hard, and the 49ers don't have the offensive firepower to really pull away from opponents. Give me the points.

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Randy’s Pick Arizona Cardinals +10.5

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The pick in this article is the opinion of the writer, not a Pick Dawgz site consensus.