Arizona Cardinals vs. San Francisco 49ers - 10/31/19 NFL Pick, Odds, and Prediction

Arizona Cardinals vs. San Francisco 49ers - 10/31/19 NFL Pick, Odds, and Prediction Photo by Matt Kartozian-USA TODAY Sports

San Francisco 49ers (7-0) at Arizona Cardinals (3-4-1)

NFL Football: Thursday, October 31, 2019 at 8:20 pm (State Farm Stadium)

The Line: Arizona Cardinals +8 -- Over/Under: 44.5

TV: FOX, NFL

The San Francisco 49ers and Arizona Cardinals meet Thursday in NFL action at State Farm Stadium.

The San Francisco 49ers look for another win to improve to 8-0 and remain a Super Bowl favorite. The San Francisco 49ers have won their last four road games. Jimmy Garoppolo is completing 69.8 percent of his passes for 1,489 yards, nine touchdowns and seven interceptions. Garoppolo has 13 touchdown passes in his last nine games. George Kittle and Deebo Samuel have combined for 659 receiving yards and two touchdowns while Marquise Goodwin has 11 receptions. The San Francisco 49ers ground game is averaging 181.1 yards per contest, and Matt Breida leads the way with 446 yards and one touchdown. Defensively, San Francisco is allowing 11 points and 224.4 yards per game. Fred Warner leads the San Francisco 49ers with 39 tackles, Nick Bosa has seven sacks and Richard Sherman has three interceptions.

The Arizona Cardinals look for a feel good win after splitting their last six games. The Arizona Cardinals have lost two of their last three home games. Kyler Murray is completing 63.7 percent of his passes for 1,988 yards, seven touchdowns and four interceptions. Murray enters this game with 292 career pass attempts. Larry Fitzgerald and Christian Kirk have combined for 768 receiving yards and two touchdowns while David Johnson has 30 receptions. The Arizona Cardinals ground game is averaging 116.5 yards per contest, and Johnson leads the way with 300 yards and two touchdowns. Defensively, Arizona is allowing 27.9 points and 407.1 yards per game. Jordan Hicks leads the Arizona Cardinals with 79 tackles, Chandler Jones has 8.5 sacks and Patrick Peterson has one interception.

The 49ers are 5-11 ATS in their last 16 vs. NFC, 2-5 ATS in their last 7 vs. NFC West and 5-2 ATS in their last 7 games overall. The Cardinals are 2-5 ATS in their last 7 home games, 2-6-1 ATS in their last 9 Thursday games and 4-1 ATS in their last 5 games in October. The 49ers are 9-4 ATS in their last 13 meetings in Arizona and 3-7 ATS in their last 10 meetings. The under is 22-10 in Cardinals last 32 home games. Th under is 4-1 in 49ers last 5 games overall.

The San Francisco 49ers have failed to cover five of their last eight games as a road favorite. The Arizona Cardinals have covered six of their last 10 games as a home underdog. The Cardinals have won nine of the last 10 meetings against the 49ers, not losing to their division rival since December of 2014. These are obviously a lot different teams this year and the Cardinals have had real issues moving the football when they play winning teams. The 49es have done nothing but display the best defense in the league and have been profitable against the number while winning these games as well. Underdogs have thrived on Thursday night, but I'll still take the 49ers by double digits.

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Randy’s Pick San Francisco 49ers -8

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The pick in this article is the opinion of the writer, not a Pick Dawgz site consensus.