San Francisco 49ers vs. Carolina Panthers - 10/27/19 NFL Pick, Odds, and Prediction

San Francisco 49ers vs. Carolina Panthers - 10/27/19 NFL Pick, Odds, and Prediction Photo by Tommy Gilligan-USA TODAY Sports

Carolina Panthers (4-2) at San Francisco 49ers (6-0)

NFL Football: Sunday, October 27, 2019 at 4:05 pm (Levi's Stadium)

The Line: San Francisco 49ers -5.5 -- Over/Under: 41

TV: FOX

The Carolina Panthers and San Francisco 49ers meet Sunday in NFL action at Levi's Stadium.

The Carolina Panthers look for another win to build on their four-game winning streak. The Carolina Panthers have split their last eight road games. Kyle Allen is completing 65.6 percent of his passes for 901 yards, seven touchdowns and zero interceptions. Allen enter this game with 122 career pass attempts under his belt. DJ Moore and Christian McCaffrey have combined for 730 receiving yards and three touchdowns while Curtis Samuel has 23 receptions. The Carolina Panthers ground game is averaging 129.5 yards per contest, and McCaffrey leads the way with 618 yards and seven touchdowns. Defensively, Carolina is allowing 22.2 points and 344 yards per game. Luke Kuechly leads the Carolina Panthers with 62 tackles, Mario Addison has 6.5 sacks and James Bradberry has three interceptions.

The San Francisco 49ers look for another win to improve to 7-0 on the season and stay as a legit Super Bowl threat. The San Francisco 49ers have won five of their last seven home games. Jimmy Garoppolo is completing 68.3 percent of his passes for 1,314 yards, seven touchdowns and six interceptions. Garoppolo has 11 touchdown passes in his last eight games. George Kittle and Marquise Goodwin have combined for 557 receiving yards and two touchdowns while Deebo Samuel has 15 receptions. The San Francisco 49ers ground game is averaging 172.7 yards per contest, and Matt Breida leads the way with 411 yards and one touchdown. Defensively, San Francisco is allowing 10.7 points and 223.5 yards per game. Fred Warner leads the San Francisco 49ers with 33 tackles, Dee Ford has 4.5 sacks and Richard Sherman has two interceptions.

The Panthers are 4-0 ATS in their last 4 road games, 4-1 ATS in their last 5 games following a bye week and 4-0 ATS in their last 4 games overall. The 49ers are 8-17 ATS in their last 25 home games, 5-12 ATS in their last 17 games in October and 4-11 ATS in their last 15 vs. NFC. The Panthers are 9-1 ATS in their last 10 meetings in San Francisco and 14-3 ATS in their last 17 meetings. The under is 4-0 in 49ers last 4 games overall. The over is 5-2 in Panthers last 7 games overall.

The Carolina Panthers have covered 10 of their last 14 games as a road underdog. The San Francisco 49ers have failed to cover 16 of their last 18 games as a home favorite. The San Francisco 49ers continue to win games and have done so with most of their contests taking place on the road, and they have the best defense in the league right now. However, the 49ers have a rough history of failing to cover home games as a favorite and the trend is so lengthy that it scares you away. The Carolina Panthers have been a different team with Allen at quarterback, and they've had an extra week to prepare and get guys back from injury. I'll lean toward the Panthers and the free points. 

Randy’s Pick Carolina Panthers +5.5

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The pick in this article is the opinion of its writer, not a Pick Dawgz site consensus.