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San Antonio Spurs vs Portland Trail Blazers Prediction 11/26/2025 Today’s NBA Picks

Nov 23, 2025; Phoenix, Arizona, USA; San Antonio Spurs guard Devin Vassell (24) grabs a pass in the second half of the game at Mortgage Match Up Center. Mandatory Credit: Arianna Grainey-Imagn Images

Nov 23, 2025; Phoenix, Arizona, USA; San Antonio Spurs guard Devin Vassell (24) grabs a pass in the second half of the game at Mortgage Match Up Center. Mandatory Credit: Arianna Grainey-Imagn Images

MATCHUP San Antonio Spurs Portland Trailblazers
Team Records 11-5 8-10
Spread +1.5 -118 -1.5 -102
Moneyline -105 -115
Total Over 240.5 (-110) Under 240.5 (-110)
Where Moda Center, Portland, OR
When Wednesday, November 26, 2025
Time 10:00 PM EST
TV KUNP 16

The San Antonio Spurs and Portland Trail Blazers meet Wednesday in NBA action at the Moda Center. Here’s a San Antonio Spurs vs Portland Trail Blazers Prediction. This article will include a San Antonio Spurs vs Portland Trail Blazers Pick.

San Antonio Spurs Betting Preview

The San Antonio Spurs beat the Hawks, lost to the Suns, and they play the Nuggets next. The Spurs have won 10 of their last 16 games.

The San Antonio Spurs are averaging 119.3 points on 49.8 percent shooting and allowing 112.3 points on 45.1 percent shooting. Victor Wembanyama is averaging 26.2 points and 12.9 rebounds, while De’Aaron Fox is averaging 23.1 points and 6.6 assists. Stephon Castle is the third double-digit scorer and Dylan Harper is dishing 3.8 assists. The San Antonio Spurs are shooting 36.6 percent from beyond the arc and 78.8 percent from the free throw line. The San Antonio Spurs are allowing 39.4 percent shooting from deep and are grabbing 45.1 rebounds per game.

Portland Trail Blazers Betting Preview

The Portland Trail Blazers lost to the Thunder, beat the Bucks, and they play the Thunder next. The Trail Blazers have lost 8 of their last 12 games.

The Portland Trail Blazers are averaging 121.2 points on 45 percent shooting and allowing 122.5 points on 48.7 percent shooting. Deni Avdija is averaging 25.9 points and 6.7 rebounds, while Shaedon Sharpe is averaging 22.6 points and 5 rebounds. Jerami Grant is the third double-digit scorer and Jrue Holiday is grabbing 5.3 rebounds. The Portland Trail Blazers are shooting 32.6 percent from beyond the arc and 81.1 percent from the free-throw line. The Portland Trail Blazers are allowing 36.7 percent shooting from deep and are grabbing 45.4 rebounds per game.

Why the Portland Trail Blazers will win

Why the San Antonio Spurs will win

Total Points Facts

Portland Trail Blazers Player Facts

San Antonio Spurs Player Facts

Matchup/League Facts

San Antonio Spurs vs Portland Trail Blazers Injury Report

The Trail Blazers will be without Damian Lillard, Blake Wesley, Jrue Holiday, Matisse Thybulle, and Scoot Henderson. Shaedon Sharpe is questionable.

The Spurs will be without Jordan McLaughlin, Victor Wembanyama, and Stephon Castle. Dylan Harper is questionable with a calf issue.

San Antonio Spurs vs Portland Trail Blazers Prediction

The Trail Blazers are going to get the benefit of the doubt because they’re at home, but they’re in such a funk right now and so banged up, I have trouble backing them as a favorite. The Spurs have injuries of their own, but they’re still finding ways to win and can score the ball at an above average clip. The Spurs could also get a boost in this game with the potential return of Dylan Harper, who is questionable instead of out at the time of this writing. The Spurs have won 6 of the last 8 games against the Trail Blazers. I’ll grab the bucket.

Randy Chambers's Pick: San Antonio Spurs +1.5

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