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San Antonio Spurs vs Los Angeles Lakers Prediction 11/5/2025 Today’s NBA Picks

Nov 3, 2025; Portland, Oregon, USA; Los Angeles Lakers guard Nick Smith Jr. (20) celebrates with teammate forward Jake LaRavia (12) after a game against the Portland Trail Blazers at Moda Center. Mandatory Credit: Troy Wayrynen-Imagn Images

Nov 3, 2025; Portland, Oregon, USA; Los Angeles Lakers guard Nick Smith Jr. (20) celebrates with teammate forward Jake LaRavia (12) after a game against the Portland Trail Blazers at Moda Center. Mandatory Credit: Troy Wayrynen-Imagn Images

MATCHUP San Antonio Spurs Los Angeles Lakers
Team Records 5-1 6-2
Where crypto.com Arena, Los Angeles, CA
When Wednesday, November 5, 2025
Time 10:00 PM EST
TV ESPN

The San Antonio Spurs and LA Lakers meet Wednesday in NBA action at the crypto.com Arena. Here’s a San Antonio Spurs vs Los Angeles Lakers Prediction. This article will include a San Antonio Spurs vs Los Angeles Lakers Pick.

San Antonio Spurs Betting Preview

The San Antonio Spurs beat the Heat, lost to the Suns, and they play the Rockets next. The Spurs have won 5 of their last 6 games.

The San Antonio Spurs are averaging 118.3 points on 49.8 percent shooting and allowing 108.3 points on 44.5 percent shooting. Victor Wembanyama is averaging 26.7 points and 13.7 rebounds, while Stephon Castle is averaging 20 points and 5.3 assists. Devin Vassell is the third double-digit scorer and Dylan Harper is dishing 3.8 assists. The San Antonio Spurs are shooting 35.2 percent from beyond the arc and 73.8 percent from the free throw line. The San Antonio Spurs are allowing 39.3 percent shooting from deep and are grabbing 47.8 rebounds per game.

LA Lakers Betting Preview

The LA Lakers beat the Heat and Trail Blazers, and they play the Hawks next. The Lakers have won 12 of their last 17 regular season games.

The LA Lakers are averaging 119.8 points on 52.9 percent shooting and allowing 116.8 points on 47.3 percent shooting. Luka Doncic is averaging 41.3 points and 11.5 rebounds, while Austin Reaves is averaging 31.1 points and 5.1 rebounds. Rui Hachimura is the third double-digit scorer, and Deandre Ayton is grabbing 8.1 rebounds. The LA Lakers are shooting 33.1 percent from beyond the arc and 79.2 percent from the free-throw line. The LA Lakers are allowing 34.9 percent shooting from deep and are grabbing 40.1 rebounds per game.

Why the Los Angeles Lakers will win

Why the San Antonio Spurs will win

Total Points Facts

Los Angeles Lakers Player Facts

San Antonio Spurs Player Facts

Matchup/League Facts

San Antonio Spurs vs Los Angeles Lakers Injury Report

The Lakers will be without Adou Thiero, Gabe Vincent, Maxi Kleber, and LeBron James. Austin Reaves is questionable with a groin issue.

The Spurs will be without Kelly Olynyk, Dylan Harper, De’Aaron Fox, and Luke Kornet. Jeremy Sochan and Lindy Waters III are questionable.

San Antonio Spurs vs Los Angeles Lakers Prediction

The Spurs in the underdog role is appealing when you consider this start, but at some point all of their injuries catch up to them, and now we’re seeing Dylan Harper on the report as well. The Lakers are playing great ball despite their issues, and that includes a 6-2 SU and ATS record. Obviously, I’d like to see the status of Reaves before locking in something, but this chalk is soft. I have to lean Lakers with the way they keep finding ways to win regular season games dating back to last season.

Randy Chambers's Pick: Los Angeles Lakers -2.5

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