San Antonio Spurs vs Dallas Mavericks Prediction 10/22/2025 Today’s NBA Picks

The San Antonio Spurs and Dallas Mavericks meet Wednesday in NBA action at the American Airlines Center. Here’s a San Antonio Spurs vs Dallas Mavericks Prediction. This article will include a San Antonio Spurs vs Dallas Mavericks Pick.

San Antonio Spurs Betting Preview

The San Antonio Spurs won 34 games last year and haven’t made the playoffs since the 2018-19 season. This will be the first time the Spurs start the season without Gregg Popovich as head coach in a million years.

The Spurs are an intriguing roster that should be able to end their playoff drought if things go well. Victor Wembanyama is one of the best players in the league, while Devin Vassell and Stephon Castle are two underrated productive players. The Spurs will have a full season of De’Aaron Fox, and hopefully he can get comfortable and live up to the upside people had hoped when traded from the Kings. Dylan Harper is one of the more intriguing rookies, and Julian Champagnie seems to have gotten better each season. Harrison Barnes remains the veteran who doesn’t get much attention but keeps producing. On paper, the Spurs should be pushing for a playoff spot, ending the drought.

Dallas Mavericks Betting Preview

The Dallas Mavericks won 39 games last season and missed the playoffs. The Mavs have missed the postseason in 2 of the last 3 years.

The Mavericks will break out their new roster with everybody healthy, which was their downfall last year. Anthony Davis, Dereck Lively II, PJ Washington, and Daniel Gafford create one of the best defensive front courts in the league. The addition of D’Angelo Russell provides an offensive spark while Kyrie Irving is out, while drafting Cooper Flagg could raise the ceiling of this group. The Mavs were already a legit playoff team when healthy, and now they added the supposed best player in the draft. The Mavericks play defense, have size, and there’s scoring with the potential return of Kyrie. Fans still aren’t pleased with the Luka trade, but this group can do some things.

Why the Dallas Mavericks will win

• The Mavericks have won each of their last seven night games against the Spurs at American Airlines Center.
• The Spurs have lost 10 of their last 11 night games at American Airlines Center.
• The Spurs have failed to cover the spread in seven of their last eight games as road underdogs against Southwest Division opponents.
• The Mavericks have covered the spread in each of their last four home games against the Spurs.

Why the San Antonio Spurs will win

• The Mavericks have lost each of their last four games against Southwest Division opponents.
• The Spurs have won 18 of their last 22 season openers against Western Conference opponents.
• The Mavericks have failed to cover the spread in each of their last four games against Southwest Division opponents.
• The Spurs have covered the spread in three of their last four games.

Total Points Facts

• Each of the Spurs’ last seven season openers against Western Conference opponents have gone OVER the total points line.
• Each of the Mavericks’ last five games against Southwest Division opponents have gone OVER the total points line.

San Antonio Spurs vs Dallas Mavericks Injury Report

The Mavericks will be without Kyrie Irving and Dante Exum. Daniel Gafford is doubtful with an ankle injury.

The Spurs will be without Kelly Olynyk, Lindy Waters III, and Jeremy Sochan. De’Aaron Fox is doubtful with a hamstring injury.

San Antonio Spurs vs Dallas Mavericks Prediction

This line is surprising when you consider the Mavericks are healthy outside of Kyrie and Gafford. There’s still the core of this team that’s capable of winning games. The Spurs have yet to prove they’re a winner and there are a handful of injuries already, including Fox, who is supposed to be a major piece of their team. The Mavs have won 8 of the last 10 games against the Spurs and have covered 7 of those games. The Mavs are a good team defensively, and AD is capable of taking over whenever he wants. This line feels soft. I’ll gladly take the Mavericks in what should be one of the stronger plays on Wednesday.