Detroit (0-0) vs Chicago (0-0)
October 22, 2025 at 08:00 PM EDT
The Line: Betting Odds: Chicago +4 — Over/Under: +232.5
The Chicago Bulls play host to the Detroit Pistons duke it out at the United Center on Wednesday night. Here’s a Detroit Pistons vs Chicago Bulls Prediction. This article will include a Detroit Pistons vs Chicago Bulls Pick.
Detroit Pistons Betting Preview
The Detroit Pistons have plenty of reasons to be optimistic after racking up 44 wins last season to go from a bottom feeder into a playoff team. Sure, the Pistons got dropped in the first round after battling their way through the Play-In Tournament, but they managed to force a series decider against the Knicks to finish as one of the surprise packages of the entire league. Cade Cunningham led from the front with averages of 26.1 points, 6.1 rebounds, and 9.1 assists per game.
Jaden Ivey averaged 17.6 points during the 30 games he played. Malik Beasley played all 82 games to average 16.3 points per game. Tobias Harris averaged 13.7 points, while Jalen Duren averaged 11.8 points and 10.3 rebounds per game. As a team, the Pistons scored 115.5 points per game while shooting 47.6 percent from the field and 36.2 percent from the 3-point line. The Pistons traded away Simone Fontecchio, Tim Hardaway Jr and Dennis Schroder while adding Javonte Green, Caris LeVert and sharpshooter Duncan Robinson.
Chicago Bulls Betting Preview
Meanwhile, the Chicago Bulls endured a slow start last season, but they finished strong to finish with a 39-43 overall record before they got eliminated in the Play-In Tournament. Coby White was a bright spot for the Bulls as he averaged 20.4 points and 4.5 assists per game. Nikola Vucevic averaged 18.5 points, 10.1 rebounds and 3.5 assists per game while Josh Giddey averaged 14.6 points, 8.1 rebounds and 7.2 assists per game, which earned him a lucrative four-year contract extension.
As a team, the Bulls scored 117.8 points per game while shooting 47.0 percent from the field and 36.7 percent from the 3-point line. Zach LaVine led the team in scoring as he averaged 24.0 points per game before he was traded midseason along with Lonzo Ball. That only sparked the Bulls, who won 15 of their final 20 games to earn the 10th seed in the Eastern Conference. Interestingly, the Bulls transitioned from one of the slowest teams in the league in terms of pace to become the fastest team, which really complimented their young roster.
Why the Chicago Bulls will win
- The Pistons have lost each of their last four games as favorites against Eastern Conference opponents.
- The Bulls have won four of their last five games as underdogs against Eastern Conference opponents.
- The Pistons have failed to cover the spread in each of their last four games as favorites against Eastern Conference opponents.
- The Bulls have covered the spread in five of their last six home games against Eastern Conference opponents.
Why the Detroit Pistons will win
- The Bulls have lost seven of their last eight games against Central Division opponents.
- The favorites have won 13 of the last 14 games between the Pistons and Bulls at United Center.
- The favorites have covered the spread in 11 of the last 12 games between the Pistons and Bulls at United Center.
- The Bulls have failed to cover the spread in seven of their last eight games as underdogs against Central Division opponents.
Total Points Facts
- Four of the Pistons’ last five road openers have gone UNDER the total points line.
- Each of the Bulls’ last three games have gone UNDER the total points line.
Detroit Pistons vs Chicago Bulls Prediction
The Pistons are going to be shorthanded to start their season with Jaden Ivey still ruled out following his arthroscopic procedure, while the Bulls have already ruled out Coby White and Zach Collins for this one.
We should be in for a tight contest in this matchup, but with the Bulls missing their leading scorer in White. I prefer a play on the Pistons to come away with the win and cover on the road at this short line.