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Cleveland Cavaliers vs Boston Celtics Prediction 10/29/2025 Today’s NBA Picks

Oct 27, 2025; New Orleans, Louisiana, USA; Boston Celtics forward Sam Hauser (30) reacts after making a three point basket against the New Orleans Pelicans during the second half at Smoothie King Center. Mandatory Credit: Matthew Hinton-Imagn Images

Oct 27, 2025; New Orleans, Louisiana, USA; Boston Celtics forward Sam Hauser (30) reacts after making a three point basket against the New Orleans Pelicans during the second half at Smoothie King Center. Mandatory Credit: Matthew Hinton-Imagn Images

MATCHUP Cleveland Cavaliers Boston Celtics
Team Records 3-2 2-3
Where TD Garden, Boston, MA
When Wednesday, October 29, 2025
Time 07:00 PM EDT
TV ESPN

The Cleveland Cavaliers travel to the TD Garden to take on the Boston Celtics on Wednesday night. Here’s a Celtics vs Cavaliers Prediction. This article will include a Celtics vs Cavaliers Prediction Pick.

Cleveland Cavaliers Betting Preview 

The Cleveland Cavaliers are starting to heat up now as they will be aiming for a fourth straight victory after smashing the Pistons in a 116-95 road win on Monday. Donovan Mitchell led the team with 35 points on 13 of 18 shooting, Jarrett Allen added 20 points on seven of 12 shooting, Evan Mobley tallied 15 points with 11 rebounds and five assists, while De’Andre Hunter chipped in with 13 points, five rebounds and six assists.

As a team, the Cavaliers shot 45 percent from the field and 11 of 35 from the 3-point line as they jumped all over the Pistons from the start and were always in control after winning the first half by 63-41. The Cavaliers actually led by as many as 35 points in this one before they started resting their starters early. 

Boston Celtics Betting Preview 

Meanwhile, the Boston Celtics will be feeling much better after snapping a three-game skid with a 122-90 road win over the Pelicans on Monday. Anfernee Simons led the team with 25 points on nine of 17 shooting off the bench. Payton Pritchard added 18 points with eight assists, while Jaylen Brown chipped in with just 15 points in 24 minutes of action as he was hampered by a hamstring injury.

As a team, the Celtics shot 48 percent from the field and 18 of 53 from the 3-point line as they set the tone with 34 points in the first quarter to take an 11-point lead into halftime. Before they absolutely dominated the fourth quarter by 35-12 to finally get their first win of the season.

Why the Boston Celtics will win

Why the Cleveland Cavaliers will win

Total Points Facts

Boston Celtics Player Facts

Cleveland Cavaliers Player Facts

Matchup/League Facts

Celtics vs Cavaliers Prediction

The Cavaliers are still missing Max Strus, Darius Garland and now Sam Merrill, while the Celtics have decided to list Jaylen Brown as probable despite his hamstring niggle. The Cavaliers look to be building nicely with three wins on the trot and they were dominant in their big win over the Pistons. Meanwhile, the Celtics were able to avoid a fourth straight defeat with an easy win over the Pelicans.

I wouldn’t be surprised if the Celtics pulled off the upset at home, but the Cavaliers are certainly playing better at this early stage of the season, and I think they get the job done at the short line.

Randy Chambers's Pick: Cleveland -4.5

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