Cleveland Cavaliers vs San Antonio Spurs Prediction 4/4/25 NBA Picks

San Antonio Spurs (32-44) vs Cleveland Cavaliers (61-15)

Game Info: Friday, April 4, 2025 at 8:00 pm (Frost Bank Center)

Betting Odds: San Antonio Spurs +13.5 -- Over/Under: 241 Click Here for the Latest Odds

Where to Watch: KENS 5

The Cleveland Cavaliers and San Antonio Spurs meet Friday in NBA action at the Frost Bank Center. Here’s a Cleveland Cavaliers vs San Antonio Spurs Prediction. This article will include a Cleveland Cavaliers vs San Antonio Spurs Pick.

Cleveland Cavaliers Betting Preview 

The Cleveland Cavaliers beat the Clippers and Knicks, and they play the Kings, Bulls, and Pacers next. The Cavs have won 21 of their last 16 games. 

The Cleveland Cavaliers are averaging 122.3 points on 49.2 percent shooting and allowing 111.9 points on 45.5 percent shooting. Donovan Mitchell is averaging 23.7 points and 4.8 assists, while Darius Garland is averaging 20.7 points and 6.6 assists. Evan Mobley is the third double-digit scorer, and Jarrett Allen is grabbing 10 rebounds. The Cleveland Cavaliers are shooting 38.4 percent from beyond the arc and 78.7 percent from the free-throw line. The Cleveland Cavaliers are allowing 36.1 percent shooting from deep and are grabbing 45.1 rebounds per game.

San Antonio Spurs Betting Preview 

The San Antonio Spurs lost to the Magic, beat the Nuggets, and then play the Trail Blazers, Clippers, and Warriors next. The Spurs have lost five of their last six games and are four games out of the play-in tournament. 

The San Antonio Spurs are averaging 114.2 points on 46.5 percent shooting and allowing 116.8 points on 47.5 percent shooting. Devin Vassell is averaging 16.5 points and 4 rebounds, while Stephon Castle is averaging 14.2 points and 3.7 assists. Keldon Johnson is the third double-digit scorer, and Harrison Barnes is dishing out 1.7 assists. The San Antonio Spurs are shooting 35.5 percent from beyond the arc and 77.4 percent from the free-throw line. The San Antonio Spurs are allowing 36.3 percent shooting from deep and are grabbing 43.7 rebounds per game.

Why the San Antonio Spurs will win

  • The Spurs have won each of their last six night games against the Cavaliers following a road win.
  • The Cavaliers have lost five of their six previous games at Frost Bank Center following a home win.
  • The Spurs have covered the spread in each of their last four games at Frost Bank Center against Eastern Conference opponents that held a winning record.
  • The Cavaliers have failed to cover the spread in five of their last six night games against teams that held a losing record.

Why the Cleveland Cavaliers will win

  • The Spurs have lost each of their last 10 games as underdogs following a win.
  • The Cavaliers have won each of their last seven games against Western Conference opponents following a win.
  • The Spurs have failed to cover the spread in 10 of their last 11 games as underdogs after winning as underdogs.
  • The road team has covered the spread in each of the last four games between the Cavaliers and Spurs.

Matchup/League Facts

  • The Spurs rank 28th in the league for opponent rebounds per game this season (46.2).
  • The Spurs rank 3rd in the league for opponent free throws made per game this season (14.6).
  • The Cavaliers rank 1st in the league for Q4 points per game this season (29.8).
  • The Cavaliers rank 1st in the league for H2 points per game this season (60.9).

Cleveland Cavaliers vs San Antonio Spurs Injury Report

The San Antonio Spurs will be without Riley Minix, Jeremy Sochan, De’Aaron Fox, Victor Wembanyama, and Charles Bassey. 

The Cavs will be without Ty Jerome and Dean Wade.

Cleveland Cavaliers vs San Antonio Spurs Prediction

The Cavs obviously have the ability to blow the doors off and they’re still a profitable 45-30-1 ATS on the season. However, the Cavs have been shaky over these last few weeks and there’s no reason to go hard anymore after losing the top seed to the Thunder. The Cavs have failed to cover seven of their last 10 games. Also, the Cavs have failed to cover six of their last nine games as a double-digit favorite. The Cavs are pretty much locked into the top seed in the East and the second seed in the NBA, so I question the motivation to lay the wood to an undermanned Spurs team. I’ll grab the points.

Randy’s Pick San Antonio Spurs +13.5

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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