Orlando City SC will visit St. Louis City SC on Wednesday, June 25^th, 2025, at the Energizer Park in this Week 19 Major League Soccer matchup. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Orlando City SC vs St. Louis City SC Prediction. We will examine:
St. Louis City SC recent form and player performance
Orlando City SC recent form and player performance
Recent betting trends and streaks involving St. Louis City SC
Recent betting trends and streaks involving Orlando City SC
Recent betting trends in games played between the Orlando City SC and St. Louis City SC
A summary that ties it all together and produces a favorable betting outcome for the Orlando City SC vs St. Louis City SC game

St. Louis City SC Preview

St. Louis City has 15 points this season and are sitting on the second to last place of the Western Conference. St. Louis City has a 3-9-6 record this season and are 2-3-4 at home. St. Louis City is coming off a 3-3 home draw against the LA Galaxy, and are 1-4-1 in their last 6 games. Over is 7-1 in their last 8 games.

St. Louis City is averaging 0.94 goals per game, while allowing 1.44 goals per game. Cedric Teuchert leads St. Louis City’s offense this season, with 3 total goals.

Orlando City SC Preview

Orlando City has 30 points this season and are sitting on the 5^th place of the Eastern Conference. Orlando City has an 8-4-6 record this season, while having a 3-2-4 road record. Orlando City is coming off a 1-0 road victory over Colorado, which snapped their previous two-game losing streak. Over is 7-2 in their last 9 games.

Orlando City is averaging 1.78 goals per game, while allowing 1.22 goals per game. Martín Ojeda is the top scorer for Orlando City this season with 8 total goals, and he is also the team’s top passer, with 4 total assists.

Why St. Louis City SC will win

The home team has won four of St. Louis CITY SC’s last five MLS games.

Why Orlando City SC will win

Orlando City SC has won four of its last six MLS games.
Orlando City SC has won six of its last nine MLS games as an away favorite following a win.
St. Louis CITY SC has lost four of its last five MLS night games.
St. Louis CITY SC has lost seven of its last eight MLS night games as an underdog.
St. Louis CITY SC has lost each of its last five MLS games as an underdog.
St. Louis CITY SC has lost eight of its last 10 MLS games as an underdog.

Total Points Facts

The ‘Both Teams to Score’ market has hit in each of St. Louis CITY SC’s last four MLS home games.
The ‘Both Teams to Score’ market has failed to hit in five of Orlando City SC’s last six MLS away games.
The ‘Over 2.5 Goals’ market has hit in eight of St. Louis CITY SC’s last nine MLS games.
The ‘Over 2.5 Goals’ market has hit in each of St. Louis CITY SC’s last four MLS home games.

Orlando City SC vs St. Louis City SC Prediction

In their only previous meeting back in 2023, Orlando won 2-1 at home.

In this Orlando City SC vs St. Louis City SC Prediction, Orlando is coming as +120 road favorites. Orlando City is rightfully favored, as they have twice as many points than Saint Louis, and they have been good on the road lately, as they have only one loss in their last nine road games. They are 3-1 straight up in their last 4 road games, while St. Louis City has been undefeated in five of their last six at home, so I see no value on either side.

Both teams have been playing some higher-scoring games lately, as they are 14-3 to the over in their last 17 games combined, mainly because of their weak defenses, which they allow 3.22 goals per game combined. I expect another high-scoring affair today, so take the over 3 goals in this one.

Nikos Lagouretos's Pick: Over 3