Houston Dynamo will visit San Diego FC on Saturday, July 5^th, 2025, at the Snapdragon Stadium this Week 21 Major League Soccer matchup. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Dynamo vs San Diego FC Prediction. We will examine:
San Diego FC recent form and player performance
Houston Dynamo recent form and player performance
Recent betting trends and streaks involving San Diego FC
Recent betting trends and streaks involving Houston Dynamo
Recent betting trends in games played between the Houston Dynamo and San Diego FC
A summary that ties it all together and produces a favorable betting outcome for the Houston Dynamo vs San Diego FC game

San Diego FC Preview

San Diego has 39 points this season and are sitting on the first place of the Western Conference. San Diego has a 12-5-3 record this season, and have a 6-1-3 home record. San Diego is coming off a 3-2 road victory over Dallas, and are 8-1-1 in their last 10 games and 6-1-1 in their last 8 home games. Over is 3-0 in their last 3 games. 

San Diego is averaging 2.05 goals per game, while allowing 1.25 goals per game. Milan Iloski is the top scorer for San Diego this season with 9 total goals.

Houston Dynamo Preview

Houston has 23 points this season and are tied with Sporting Kansas City on the 10^th place of the Western Conference. Houston has a 6-9-5 record this season and are 2-3-4 on the road. Houston is coming off a 1-0 home victory over Saint Louis City, which snapped their previous three-game losing streak. Over is 6-1 in their 7 games. 

Houston is averaging 1.21 goals per game, while allowing 1.63 goals per game. Ezequiel Ponce leads Houston’s offense this season with 4 total goals.

Why San Diego FC will win

San Diego FC has won each of its last four MLS games.
San Diego FC has won five of its last six MLS games.
San Diego FC has won four of its last five MLS home games.
San Diego FC has won five of its last seven MLS games following a win.
Houston has lost three of its last four MLS games.
The favorite has won four of San Diego FC’s last five MLS games at Snapdragon Stadium.
The favorite has won seven of San Diego FC’s last 10 MLS games.

Total Points Facts

The ‘Both Teams to Score’ market has failed to hit in four of San Diego FC’s last five MLS home games.
The ‘Both Teams to Score’ market has hit in three of Houston’s last four MLS games.
The ‘Over 3.5 Goals’ market has hit in each of San Diego FC’s last three MLS games.
The ‘Over 4.5 Goals’ market has hit in each of San Diego FC’s last three MLS games.
The ‘Over 2.5 Goals’ market has hit in five of Houston’s last six MLS games.

Houston Dynamo vs San Diego FC Prediction

In this Houston Dynamo vs San Diego FC Prediction, San Diego is coming as -155 home favorites. San Diego is rightfully favored, as they have more points this season, and have been in excellent form lately, with 8 wins in their last 10 overall games and 6 wins in their last 8 home games. Houston on the other hand, has been mediocre this season, and have been in poor form lately, with just one win in their last four games. San Diego is also superior both offensively and defensively, so I expect them to dominate this game and get away with the home victory.

Nikos Lagouretos's Pick: San Diego FC -155