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Inter Miami CF vs Chicago Fire Prediction 7/22/2026 Picks

Sep 30, 2025; Fort Lauderdale, Florida, USA; Inter Miami CF forward Lionel Messi (10) dribbles the ball against Chicago Fire during the second half at Chase Stadium. Mandatory Credit: Sam Navarro-Imagn Images

Sep 30, 2025; Fort Lauderdale, Florida, USA; Inter Miami CF forward Lionel Messi (10) dribbles the ball against Chicago Fire during the second half at Chase Stadium. Mandatory Credit: Sam Navarro-Imagn Images

MATCHUP Chicago Fire Inter Miami CF Inter Miami CF
Team Records 8-2-4 9-4-2
Where Miami Freedom Park
When Wednesday, July 22, 2026
Time 07:30 PM EDT
TV Apple TV
In this article, we will formulate a Chicago Fire vs Inter Miami Prediction for this MLS game on Wednesday, July 22nd. Let’s take a look at the prediction for this MLS matchup.

Inter Miami Preview


Inter Miami has 31 points this season with a 9-2-4 record, and sits in 2nd place of the Eastern Conference. They have a 2-1-3 home record and a 7-1-1 away record. Inter Miami is coming off a 6-4 win against Philadelphia at home, where they had 64% possession of the ball and 17 total shots, 10 of them on target. They had 85% completed passes, and more expected goals, with 5.51 compared to Philadelphia’s 3.95.

Inter Miami is scoring 2.60 goals per game, which ranks 1st in MLS, while allowing 1.87 goals per game, which ranks 20th in MLS. Lionel Messi is Inter Miami’s top scorer with 12 goals, followed by Germán Berterame with 7 goals and Luis Suárez with 6 goals. Lionel Messi is Inter Miami’s top passer, with 8 assists.

Chicago Fire Preview


Chicago has 26 points this season with a 8-4-2 record, and sits in 3rd place of the Eastern Conference. They have a 5-3-0 home record and a 3-1-2 away record. Chicago is coming off a 2-1 win against Toronto at home, where they had 53% possession of the ball and 15 total shots, 6 of them on target. They had 86% completed passes, and more expected goals, with 1.77 compared to Toronto’s 1.39.

Chicago is scoring 1.93 goals per game, which ranks 8th in MLS, while allowing 1.14 goals per game, which ranks 5th in MLS. Hugo Cuypers is Chicago’s top scorer with 13 goals, followed by Philip Zinckernagel with 5 goals and Maren Haile-Selassie with 3 goals. Philip Zinckernagel is Chicago’s top passer, with 7 assists.

Chicago Fire vs Inter Miami Prediction


Both teams are a perfectly balanced 2-2-1 in their last 5 meetings and the over is 6-1 in their last 7 meetings. They are also 2-2-1 in their last 5 meetings in Miami and the over is 4-1 in those 5 games.

In this Chicago Fire vs Inter Miami Prediction, Inter Miami is coming as +100 home favorites. Both teams are coming into this matchup in excellent form, having won their last four and three games respectively and I cannot fade Chicago Fire at this point, as they have been undefeated in 11 of their last 12 games on the road. Both teams have been playing some high-scoring games lately, as they are 13-1 to the over 2.5 in their last 14 games combined and the over is also a strong trend in their recent meetings. Take the over 3.5 goals in this one.

Nikos Lagouretos's Pick: Over 3.5

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