Orlando City SC will visit Charlotte FC on Saturday, July 5^th, 2025, at the Bank of America Stadium in this Week 21 Major League Soccer matchup. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Orlando City SC vs Charlotte FC Prediction. We will examine:
Charlotte FC recent form and player performance
Orlando City SC recent form and player performance
Recent betting trends and streaks involving Charlotte FC
Recent betting trends and streaks involving Orlando City SC
Recent betting trends in games played between the Orlando City SC and Charlotte FC
A summary that ties it all together and produces a favorable betting outcome for the Orlando City SC vs Charlotte FC game

Charlotte FC Preview

Charlotte has 25 points this season and are sitting on the 10^th place of the Eastern Conference. Charlotte has an 8-11-1 record this season, and are 6-2 at home. Charlotte is coming off a 2-3 road defeat by Chicago Fire, and are 1-4 in their last 5 games. Over is 11-1 in their last 12 games and 5-1 in their last 6 home games. 
   
Charlotte is averaging 1.60 goals per game, while allowing 1.70 goals per game. Patrick Agyemang is the top scorer for Charlotte this season with 6 total goals.

Orlando City SC Preview

Orlando City has 33 points this season and are sitting on the 5^th place of the Eastern Conference. Orlando City has a 9-5-6 record this season, while having a 4-2-4 road record. Orlando City is coming off a 1-2 home defeat by Cincinnati, which snapped their previous two-game winning streak. They have been terrific on the road, having lost only once in their last 10 road games and over is 9-2 in their last 11 games.

Orlando City is averaging 1.85 goals per game, while allowing 1.30 goals per game. Martín Ojeda is the top scorer for Orlando City this season with 8 total goals, and he is also the team’s top passer, with 6 total assists.

Why Charlotte FC will win

Charlotte FC has won each of its last five MLS games as a home underdog following a loss.
Charlotte FC has won 10 of its last 13 MLS home games following a loss.
Charlotte FC has won six of its last nine MLS games as a home underdog.
Charlotte FC has lost nine of its last 11 MLS games.
The home team has won five of Charlotte FC’s last six MLS games.

Why Orlando City SC will win

Orlando City SC has won six of its last eight MLS night games following a loss.
Orlando City SC has won three of its last four MLS away games following a loss.
The away team has won five of Orlando City SC’s last seven MLS games.
Charlotte FC has lost each of its last three MLS games.

Total Points Facts

The ‘Both Teams to Score’ market has hit in each of Charlotte FC’s last eight MLS games as an underdog.
The ‘Both Teams to Score’ market has hit in nine of Charlotte FC’s last 10 MLS games.
The ‘Both Teams to Score’ market has hit in four of Orlando City SC’s last five MLS games.
The ‘Over 2.5 Goals’ market has hit in each of Charlotte FC’s last eight MLS games as an underdog.
The ‘Over 2.5 Goals’ market has hit in nine of Charlotte FC’s last 10 MLS games.
The ‘Over 2.5 Goals’ market has hit in nine of Orlando City SC’s last 11 MLS games as an away underdog.

Orlando City SC vs Charlotte FC Prediction

In their previous meeting this season, Orlando won 3-1 at home. Orlando is 4-1 in their last 5 overall meetings, while Charlotte is 2-0-2 in their last four home meetings against Orlando. Under is 3-1 in their last 4 meetings in Orlando.
In this Orlando City SC vs Charlotte FC Prediction, both teams are coming at a pickem price. Orlando City has more points than Charlotte, and have been almost unbeatable on the road lately, with only one loss in their last ten games on the road. Orlando is better both defensively and offensively, and have been dominating Charlotte in their recent meetings, so I like them to not lose today’s game. Take Orlando City SC PK in this one.

Nikos Lagouretos's Pick: Orlando City SC PK