White Sox vs Royals Prediction 4/10/2026 Today’s MLB Picks

In this article we will formulate a White Sox vs Royals prediction for this MLB game on Friday, April 10th at Kauffman Stadium in Kansas City, Missouri. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 5-8 this season after they won game one in this series by a score of 2-0 on Thursday night. Chicago scored once in the fourth inning and once in the seventh for the shutout win. The White Sox recorded five hits in the game and they were led by Montgomery and Acuna, who both had one RBI. Kay allowed three hits and zero earned runs over 5.2 innings for the win, while Dominguez picked up the save in the ninth. Prior to this series, Chicago lost all three against the Orioles, but did win all three against the Blue Jays before that. 

This season, Chicago has a 5.02 ERA with a 1.51 WHIP and a .255 opponent batting average, while they have scored 43 runs with a .204 batting average and a .291 on base percentage. Munetaka Murakami has led the White Sox with four home runs and seven RBIs, while Miguel Vargas has added one home run and seven RBIs. The projected starting pitcher for Chicago is Davis Martin, who is 2-0 with a 2.45 ERA and a 1.18 WHIP over 11.0 innings pitched this season. 

Kansas City Royals Betting Preview

The Kansas City Royals are 5-8 this year after they lost game one in this series by a score of 2-0 on Thursday. Kansas City pitched a very good game, but their offense couldn’t find any runs in the low scoring loss. The Royals recorded five hits and they committed one error in the game, while they were led by Garcia and Witt Jr, who both had two hits. Lugo allowed four hits and one earned run over 6.1 innings for the loss, while Morgan pitched two scoreless innings in relief. Prior to this series, Kansas City lost two out of three against the Guardians and two out of three against the Brewers. 

This season, Kansas City has a 4.35 ERA with a 1.43 WHIP and a .249 opponent batting average, while they have scored 45 runs with a .227 batting average and a .318 on base percentage. Jonathan India has led the Royals with two home runs and eight RBIs, while Kyle Isbel has added two home runs and five RBIs. The projected starting pitcher for Kansas City is Kris Bubic, who is 1-1 with a 4.09 ERA and a 1.09 WHIP over 11.0 innings pitched this year. 

Why the Kansas City Royals will win

• The White Sox have lost each of their last nine night games against the Royals at Kauffman Stadium following a win.
• The Royals have won each of their last seven night games against the White Sox following a home loss.
• The White Sox have failed to cover the run line in each of their last seven games at Kauffman Stadium following a win.
• The Royals have covered the run line in seven of their last eight games against the White Sox at Kauffman Stadium following a loss.
• The White Sox have trailed after 5 innings in seven of their last nine road games against American League opponents.

Why the Chicago White Sox will win

• The Royals have lost each of their last four games as favorites after playing the previous day.
• The underdogs have won five of the Royals’ last six games.
• The White Sox have covered the run line each of their last seven games against AL Central opponents that held a losing record.
• The Royals have failed to cover the run line in each of their last five games as favorites against AL Central opponents following a loss.
• The Royals have trailed after 5 innings in six of their last seven games as favorites against AL Central opponents.

Total Runs Facts

• Eight of the Royals’ last nine games as favorites against AL Central opponents have gone UNDER the total runs line.
• Each of the White Sox’s last four road games against AL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Royals’ last eight games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last four games as underdogs.

Kansas City Royals Player Prop Facts

• Jonathan India has hit a home run in two of his last three appearances in night games against AL teams that held a losing record.
• Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 22 games as favorites against the White Sox.
• Kris Bubic has recorded six or more strikeouts in seven of his last nine appearances with the Royals as home favorites.
• Kris Bubic has recorded a win in nine of his last 12 appearances against opponents that held a losing record.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit at least one home run in four of his last 14 appearances in night games.
• Austin Hays has recorded at least one hit in 10 of his last 11 appearances with his team as an underdog against AL opponents.

White Sox vs Royals Prediction 

Chicago bounced back from their series sweep against the Orioles with a win in game one to start this series, but they have scored three runs or fewer in five straight games. The White Sox are 2-5 on the road this year, while the Royals are 3-4 at home. Kansas City has lost three in a row and they have scored a total of three runs in those three games. I don’t trust either offense in this matchup, but Bubic gives us more upside on the mound. Take the Royals -1.5 here.

David Racey's Pick: Royals -1.5