White Sox vs Astros Prediction 6/10/25 MLB Picks

In this article, we will formulate a White Sox vs Astros prediction for this MLB game on Tuesday, June 10th at Daikin Park in Houston, Texas. Let’s take a look at the prediction for this MLB matchup. 

Chicago White Sox Betting Preview

The Chicago White Sox are 22-44 this season after they won two out of three against Kansas City by scores of 7-2, 4-1, and 5-7. In their game three win, Chicago led 2-0 in the first inning, but they allowed the next seven runs for the loss. The White Sox recorded just four hits in the game, and they were led by Vargas, who went 1-3 with one home run and three RBIs in the loss. Chicago started Vasil, who allowed five hits and two earned runs over 3.1 innings, while Wilson allowed three earned runs in two relief innings. 

Prior to that series, the White Sox split four games with the Tigers and lost all three against the Orioles. Chicago has won three of their last four games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.12 ERA with a 1.37 WHIP and a .250 opponent batting average, while the offense has scored 233 runs with a .223 batting average and a .296 on-base percentage this season. Miguel Vargas has led Chicago with nine home runs and 29 RBIs, while Andrew Benintendi has added six home runs and 23 RBIs this year. The projected starting pitcher for Chicago is Shane Smith, who is 2-3 with a 2.45 ERA and a 1.14 WHIP over 62.1 innings pitched this season. 

Houston Astros Betting Preview

The Houston Astros are 36-29 this year after they won two out of three against Cleveland by scores of 4-2, 5-3, and 2-4. In their game three loss, Houston tied the game at two in the seventh inning, but allowed two runs in the bottom of the inning for the loss. The Astros recorded seven hits and they committed one error in the game, while they were led by Smith, who went 1-4 with two RBIs in the loss. Houston started Walter, who allowed six hits and two earned runs over 6.0 innings, while Okert picked up the loss. 

Prior to that series, the Astros won two out of three against the Pirates and split four games with the Rays. Houston has won five of their last seven games, and they are currently first in the AL West standings. The Houston pitching staff has a 3.52 ERA with a 1.16 WHIP and a .220 opponent batting average, while their offense has scored 261 runs with a .250 batting average and a .316 on-base percentage this season. Isaac Paredes has led Houston with 14 home runs and 38 RBIs, while Jeremy Pena has added nine home runs and 32 RBIs this year. The projected starting pitcher for Houston is Lance McCullers Jr., who is 1-1 with a 4.44 ERA and a 1.40 WHIP over 24.1 innings pitched this year. 

Why the Astros will beat the White Sox 

• The Astros have won each of their last 10 home games following a loss.
• The White Sox have lost each of their last eight games as road underdogs against American League opponents.
• The Astros have covered the run line in nine of their last 10 games as home favorites against American League opponents following a road loss.
• The White Sox have failed to cover the run line in five of their last six games as road underdogs against American League opponents following a home loss.
• The White Sox have trailed after 5 innings in four of their last five road games against American League opponents.
• The Astros have led after 3 innings in four of their last five games at Daikin Park against American League opponents that held a losing record.

Total Runs Facts

• Each of the White Sox’s last five night games as underdogs have gone OVER the total runs line.
• Each of the Astros’ last three night games against AL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last six games as favorites against AL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the White Sox’s last 10 night games against American League opponents.

Houston Astros Player Prop Facts

• Isaac Paredes has hit a home run in each of the Astros’ last two games as home favorites against AL Central opponents.
• Lance McCullers Jr. has recorded a win in each of his last three appearances against the White Sox at Daikin Park.
• Lance McCullers Jr. has recorded eight or more strikeouts in each of his last three home appearances against AL opponents.
• Christian Walker has scored a run in each of the Astros’ last five home games against opponents that held a losing record.
• Jose Altuve has recorded two or more hits in each of his last six home appearances after not playing the previous day.
• Jose Altuve has recorded at least one Single in each of his last nine home appearances after not playing the previous day.
• Yordan Alvarez has recorded at least one RBI in nine of his last 10 home appearances against the White Sox.

Chicago White Sox Player Prop Facts

• Luis Robert has recorded an RBI in each of the White Sox’s last three games as underdogs against AL West opponents.
• Michael A. Taylor has hit a home run in two of his last three road appearances against AL West opponents that held a winning record.
• Andrew Benintendi has recorded at least one Single in each of his four previous road appearances against the Astros after not playing the previous day.
• Michael A. Taylor has scored at least one run in each of his last four appearances with the White Sox as underdogs against AL opponents.
• Austin Slater has recorded two hits in each of his three previous appearances at Daikin Park.
• Mike Tauchman has recorded at least one Double in three of the White Sox’s last four road games.

White Sox vs Astros Prediction 

Chicago continues to play well over their last seven games, and they come into this series with plenty of momentum. The White Sox are 6-26 on the road this year, while the Astros are 22-12 at home. Houston has won three of their last four games, and they are starting McCullers, who has allowed two earned runs or fewer in three of his last four starts. The White Sox are going with Smith, who has allowed one earned run or fewer in three of his last five starts. I know Chicago has shown improvement, but they only have six road wins this year. Take Houston -1.5 here. 

David Racey's Pick: Astros -1.5