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Washington Nationals vs Pittsburgh Pirates Prediction 4/16/2026 Today’s MLB Picks

Mar 30, 2026; Cincinnati, Ohio, USA; Pittsburgh Pirates starting pitcher Braxton Ashcraft (35) pitches against the Cincinnati Reds in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Mar 30, 2026; Cincinnati, Ohio, USA; Pittsburgh Pirates starting pitcher Braxton Ashcraft (35) pitches against the Cincinnati Reds in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

MATCHUP Washington Nationals Pittsburgh Pirates
Team Records 8-10 11-7
Where PNC Park, Pittsburgh, Pennsylvania
When Thursday, April 16, 2026
Time 12:35 PM EDT
TV MLB.TV

In this article, we will formulate a Nationals vs Pirates Prediction for this MLB matchup on Thursday, April 16th in the fourth game of this series. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 11-7 record this season and are sitting in the first place of the NL Central. They have a 6-3 home record and are coming off a 2-0 home win against the Nationals. Their previous three games were a 4-5 home loss against the Nationals, a 16-5 home win, and a 6-7 road loss against the Cubs.

The Pirates have a .244 batting average this season, .337 OBP and .385 Slugging percentage. Pittsburgh’s pitching staff has a 3.25 ERA and 1.31 WHIP. Ryan O’Hearn is the team’s best hitter with a .333 batting average. Oneil Cruz leads the team in RBI with 16, and Brandon Lowe adds a team‑high 7 home runs.

Braxton Ashcraft (R) is the projected starting pitcher for the Pirates, and he has a 1-1 record, 2.12 ERA and 1.00 WHIP.

Washington Nationals Preview

The Washington Nationals have a 8-10 record this season and are sitting in the fourth place of the NL East. They have a 7-5 away record and are coming off a 0-2 road loss against the Pirates. Their previous three games were a 5-4 road win against the Pirates, a 5-16 road loss, and an 8-6 road win against the Brewers.

The Nationals have a .263 batting average this season, .337 OBP and .416 Slugging percentage. Washington’s pitching staff has a 5.89 ERA and 1.56 WHIP. CJ Abrams is the team’s best hitter with a .367 batting average, also leading the team in RBI with 19 and adding a team‑high 6 home runs.

Foster Griffin (L) is the projected starting pitcher for the Nationals, and he has a 2-0 record, 1.76 ERA and 1.11 WHIP.

Washington Nationals @ Pittsburgh Pirates Betting Trends: April 16, 2026

Why the Pittsburgh Pirates will win

Why the Washington Nationals will win

Total Runs Facts

Pittsburgh Pirates Player Prop Facts

Washington Nationals Player Prop Facts

Matchup/League Facts

Nationals vs Pirates Prediction

Both teams are tied 5-5 in their last 10 meetings but the Pirates are 4-1 in their last 5 meetings in Pittsburgh.

In this Nationals vs Pirates Prediction, the Pirates are coming as -165 home favorites. The Pirates have the 2-1 lead in this series but they are facing the leftie Foster Griffin who has been excellent this season with just one earned run in his last two starts. Braxton Ashcraft has also just two earned runs in his last two starts so I’m expecting both pitchers to keep offenses in check. Only one game of this series had more than 9 runs, so take the under 9 in this one.

Nikos Lagouretos's Pick: Under 9

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