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Washington Nationals vs Chicago Cubs Prediction 3/28/2026 Today’s MLB Picks

Mar 26, 2026; Chicago, Illinois, USA;  A Chicago Cubs fan during the seventh inning against the Washington Nationals at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

Mar 26, 2026; Chicago, Illinois, USA; A Chicago Cubs fan during the seventh inning against the Washington Nationals at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Washington Nationals Chicago Cubs
Team Records 1-0 0-1
Spread +1.5 100 -1.5 -120
Moneyline +203 -252
Total Over 8.5 (-118) Under 8.5 (-102)
Where Wrigley Field, Chicago, Illinois
When Saturday, March 28, 2026
Time 02:20 PM EDT
TV ESPN Unlmtd
The Washington Nationals and Chicago Cubs meet Saturday in MLB action at Wrigley Field. Here’s a Washington Nationals vs. Chicago Cubs Prediction. This article will include a Washington Nationals vs. Chicago Cubs Pick.

Washington Nationals Betting Preview


The Washington Nationals are 1-0 on the year and play the Phillies and Dodgers next. The Washington Nationals are batting .297 on the season and have a .350 OBP, and a .595 slugging percentage. The Washington Nationals pitching staff has a 3.00 ERA and a 1.56 WHIP. Joey Wiemer leads the Washington Nationals with 3 hits and 1 RBI, while Brady House and Andres Chaparro have combined for 4 hits and 2 RBI.

Miles Mikolas gets the ball for the Washington Nationals, and he was 8-11 with a 4.84 ERA and 100 strikeouts last season. Mikolas is 6-8 with a 3.73 ERA and 96 strikeouts in his career against the Chicago Cubs.

Chicago Cubs Betting Preview


The Chicago Cubs are 0-1 on the year and play the Angels and Guardians next. The Chicago Cubs are batting .235 on the season and have a .350 OBP, and a .294 slugging percentage. The Chicago Cubs pitching staff has an 8.00 ERA and a 1.44 WHIP. Michael Busch leads the Chicago Cubs with 3 hits and 1 RBI while Pete Crow-Armstrong and Ian Happ have combined for 3 hits and 2 RBI.

Cade Horton gets the ball for the Chicago Cubs, and he was 11-4 with a 2.67 ERA and 97 strikeouts last season. This will be Horton’s second career game against the Washington Nationals.

Why the Chicago Cubs will win

Why the Washington Nationals will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Washington Nationals Player Prop Facts

Matchup/League Facts

Washington Nationals vs Chicago Cubs Prediction


The Nationals dominate the first game and it makes the plus money attractive in this spot. However, the Cubs are simply the better team by a cofmrotble margin and I’d expect a better effort after having a couple of days to stew over that loss. Mikolas isn’t the same pitcher he was a few years ago and Horton was highly impressive as a rookie. Early start time: it would be a bad look for the Cubs to get off to an 0-2 start. I have to side with the Cubs and I’ll lay the PL to shave down the juice.

Randy Chambers's Pick: Chicago Cubs -1.5

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