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Tigers vs Reds Prediction 4/25/2026 Today’s MLB Picks

Apr 21, 2026; St. Petersburg, Florida, USA; Cincinnati Reds infielder Matt McLain (9) hits during the seventh inning against Tampa Bay Rays at Tropicana Field. Mandatory Credit: Pablo Robles-Imagn Images

Apr 21, 2026; St. Petersburg, Florida, USA; Cincinnati Reds infielder Matt McLain (9) hits during the seventh inning against Tampa Bay Rays at Tropicana Field. Mandatory Credit: Pablo Robles-Imagn Images

MATCHUP Detroit Tigers Cincinnati Reds
Team Records 14-13 17-9
Spread -1.5 141 +1.5 -171
Moneyline -110 -110
Total Over 9 (-122) Under 9 (101)
Where Great American Ball Park, Cincinnati, Ohio
When Saturday, April 25, 2026
Time 07:15 PM EDT
TV FOX
In this article we will formulate a Tigers vs Reds prediction for this MLB game on Saturday, April 25th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Detroit Tigers Betting Preview

The Detroit Tigers are 14-13 this year after they lost game one by a score of 9-8 on Friday. Detroit led 5-0 in the fourth and 8-7 in the ninth, but they couldn’t close the game for the loss. The Tigers recorded 11 hits and they committed one error in the game, while they were led by Vierling and Carpenter, who both had two RBIs. Valdez allowed four hits and two earned runs over 4.1 innings, while Jansen picked up the loss in the ninth. Prior to this series, Detroit won two out of three against the Brewers and split four games with the Red Sox. 

This season, Detroit has a 3.78 ERA with a 1.32 WHIP and a .238 opponent batting average, while they have scored 122 runs with a .249 batting average and a .331 on base percentage. Dillon Dingler has led the Tigers with five home runs and 19 RBIs, while Riley Greene has added three home runs and 17 RBIs. The projected starting pitcher for Detroit is Jack Flaherty, who is 0-1 with a 3.47 ERA and a 1.59 WHIP over 23.1 innings pitched this year. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 17-9 this season after they won game one in dramatic fashion by a score of 9-8. Cincinnati erased a 5-0 deficit in the middle innings, but they blew the save, before scoring two in the ninth for the win. The Reds recorded 11 hits in the game and they were led by McLain, who went 2-4 with two home runs and four RBIs. Abbott allowed six hits and five earned runs over 4.0 innings, while Santillan allowed three earned runs in relief. Prior to this series, Cincinnati won two out of three against the Rays and all three against the Twins. 

This season, Cincinnati has a 3.75 ERA with a 1.38 WHIP and a .233 opponent batting average, while they have scored 106 runs with a .210 batting average and a .303 on base percentage. Sal Stewart has led the Reds with eight home runs and 24 RBIs, while Elly De La Cruz has added eight home runs and 18 RBIs. The projected starting pitcher for Cincinnati is Brady Singer, who is 1-1 with a 5.32 ERA and a 1.65 WHIP over 23.2 innings pitched this season. 

Why the Cincinnati Reds will win

Why the Detroit Tigers will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

Detroit Tigers Player Prop Facts

Tigers vs Reds Prediction 

Cincinnati was able to get a comeback victory to start this series on Friday and they have one of the best records in the MLB. The Reds are 7-6 at home this year, while the Tigers are 4-11 on the road. Detroit has allowed 8+ runs in three of their last five games and they are starting Flaherty, who has allowed one earned run or fewer in three straight starts, but only went 3.1 innings last time out. Cincinnati is going with Singer, who has allowed 3, 1, and 5 earned runs in his last three starts. I think the pitching matchup is pretty even, but Cincinnati is red hot and they have a ton of momentum from Friday. Take the Reds here.

David Racey's Pick: Reds ML

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