Detroit (60-41) vs Pittsburgh (40-61)
July 22, 2025 at 06:40 PM EDT
The Line: Betting Odds: Pittsburgh +1.5 — Over/Under: +7.5
In this article, we will formulate a Tigers vs Pirates prediction for this MLB game on Tuesday, July 22nd at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup.
Detroit Tigers Betting Preview
The Detroit Tigers are 60-41 this season after they lost game one by a score of 3-0 on Monday. Detroit fell behind 3-0 in the second inning, but their offense continued to struggle in the shutout loss. The Tigers recorded five hits in the game, and they were led by Vierling, who had one hit and one walk in the loss. Detroit started Flaherty, who allowed six hits and three earned runs over 3.0 innings for the loss, while Enns pitched 2.2 scoreless innings in relief.
Prior to this series, the Tigers lost two out of three against the Rangers and all three against the Mariners. Detroit has lost seven of its last eight games, and they are currently first in the AL Central standings. The Detroit pitching staff has a 3.65 ERA with a 1.22 WHIP and a .237 opponent batting average, while the offense has scored 485 runs with a .249 batting average and a .322 on-base percentage this season. Riley Greene has led Detroit with 25 home runs and 79 RBIs, while Spencer Torkelson has added 21 home runs and 59 RBIs this year. The projected starting pitcher for Detroit is Casey Mize, who is 9-3 with a 3.15 ERA and a 1.22 WHIP over 88.2 innings pitched this season.
Pittsburgh Pirates Betting Preview
The Pittsburgh Pirates are 40-61 this year after they won game one to snap their losing streak on Monday. Pittsburgh scored three runs early in the game and they picked up the win, but failed to score over the last seven innings. The Pirates recorded nine hits in the game, and they were led by Reynolds, who went 1-4 with two RBIs in the win. Pittsburgh started Skenes, who allowed three hits and zero earned runs over 6.0 innings for the win, while Bednar picked up the save.
Prior to this series, the Pirates lost all three against the White Sox and two out of three against the Twins. Pittsburgh has lost 11 of its last 13 games, and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.85 ERA with a 1.21 WHIP and a .236 opponent batting average, while their offense has scored 336 runs with a .230 batting average and a .300 on-base percentage this season. Oneil Cruz has led Pittsburgh with 16 home runs and 39 RBIs, while Bryan Reynolds has added 10 home runs and 48 RBIs this year. The projected starting pitcher for Pittsburgh is Mitch Keller, who is 3-10 with a 3.48 ERA and a 1.14 WHIP over 119.0 innings pitched this year.
Why the Pirates will beat the Tigers
The Pirates have won each of their last 10 games at PNC Park against teams that held a winning record.
The Tigers have lost three of their last four games as favorites.
The Tigers have failed to cover the run line in each of their last eight games following a loss.
The home team has covered the run line in each of the Tigers’ last four games.
The Pirates have led after 5 innings in six of their last seven home games against opponents that held a winning record.
The Pirates have led after 3 innings in each of their last four games as home underdogs.
Why the Tigers will beat the Pirates
The Pirates have lost 10 of their last 11 home games against American League opponents following a win.
The Tigers have won seven of their last eight night games against NL Central opponents following a loss.
The Pirates have failed to cover the run line in 10 of their last 11 home games against American League opponents following a win.
The favorites have covered the run line in nine of the last 10 games between the Tigers and Pirates.
The Pirates have trailed after 5 innings in six of their last eight games as home underdogs against AL Central opponents.
Total Runs Facts
Nine of the Tigers’ last 10 games against National League opponents have gone OVER the total runs line.
Six of the Pirates’ last seven games as underdogs against the Tigers have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Pirates’ last eight games as underdogs against American League opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Tigers’ last five night games.
Pittsburgh Pirates Player Prop Facts
Andrew McCutchen has hit a home run in four of his last 10 appearances in night games against AL Central teams that held a winning record.
Mitch Keller has recorded six or more strikeouts in each of his four previous appearances against the Tigers at PNC Park.
Bryan Reynolds has recorded at least one hit in each of the Pirates’ last 17 games at PNC Park against AL Central opponents that held a winning record.
Andrew McCutchen has recorded a Double in three of the Pirates’ last four games as underdogs against the Tigers.
Mitch Keller has recorded a win in each of his last three appearances in night games against AL Central teams that held a winning record.
Detroit Tigers Player Prop Facts
Spencer Torkelson has hit a home run in each of the Tigers’ last two games as favorites against NL opponents.
Spencer Torkelson has recorded at least one hit in each of the Tigers’ last eight night games against opponents that held a losing record.
Casey Mize has recorded a win in each of his last three appearances against opponents that held a losing record.
Tigers vs Pirates Prediction
Both of these teams come into this contest really struggling in recent series, but Pittsburgh was able to get the win on Monday. The Tigers are 28-23 on the road this year, while the Pirates are 27-24 at home. Detroit is lucky to have a huge lead in the AL Central, as they have played very poorly over the last two weeks. The Tigers are starting Mize, who has allowed two earned runs or fewer in three of his last four starts. The Pirates are going with Keller, who has allowed two earned runs or fewer in five straight. We have two pitchers that are red hot and two offenses that can’t hit, so give me the under here.