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Tampa Bay Rays vs St. Louis Cardinals Prediction 3/26/2026 Today’s MLB Picks

Sep 13, 2025; Chicago, Illinois, USA; Tampa Bay Rays starting pitcher Drew Rasmussen (57) pitches against the Chicago Cubs during the first inning at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

Sep 13, 2025; Chicago, Illinois, USA; Tampa Bay Rays starting pitcher Drew Rasmussen (57) pitches against the Chicago Cubs during the first inning at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

MATCHUP Tampa Bay Rays St. Louis Cardinals
Team Records 0-0 0-0
Spread -1.5 135 +1.5 -163
Moneyline -126 +104
Total Over 8 (-101) Under 8 (-119)
Where Busch Stadium, St. Louis, Missouri
When Thursday, March 26, 2026
Time 04:15 PM EDT
TV MLB.TV

In this article, we will formulate a Rays vs Cardinals Prediction for this MLB matchup on Thursday, March 26th. Let’s take a look at the prediction for this MLB matchup.

St. Louis Cardinals Preview

The St. Louis Cardinals finished last season with a 78-84 record and were placed 4th in the NL Central. They had a 44-37 home record and were 81-73 in over/under.

Last season the Cardinals had a .245 batting average, .314 OBP and .379 Slugging percentage. St. Louis’ pitching staff had a 4.29 ERA and 1.32 WHIP. Alec Burleson led the Cardinals with 144 hits, and he was the team’s best hitter with a .290 batting average. Wilson Contreras led the team in RBI, with 80 and added a team-high 20 home runs.

Matthew Liberatore (L) is the projected starting pitcher for the Cardinals, and last season he had an 8-12 record, 4.21 ERA and 1.31 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays finished last season with a 77-85 record and were placed 4th in the AL East. They had a 41-40 home record and 36-45 away record and were 71-80-11 in over/under.

Last season the Rays had a .251 batting average, .313 OBP and .401 Slugging percentage. Tampa Bay’s pitching staff had a 3.94 ERA and 1.22 WHIP. Yandy Díaz led the Rays with 175 hits, and he was the team’s best hitter with a .300 batting average. Junior Caminero led the team in RBI, with 110 and added a team-high 45 home runs.

Drew Rasmussen (R) is the projected starting pitcher for the Rays, and last season he had a 10-5 record, 2.76 ERA and 1.02 WHIP. The Rays face off against the Brewers, Twins, and Cubs next. 

Tampa Bay Rays @ St. Louis Cardinals Betting Trends: March 26, 2026

Why the St. Louis Cardinals will win

Why the Tampa Bay Rays will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Tampa Bay Rays Player Prop Facts

Rays vs Cardinals Prediction

The Rays won the only series against the Cardinal last season by 2-1 wins at home and both teams are tied 5-5 in their last 10 meetings. Over is 3-0-1 in their last 4 meetings.

In this Rays vs Cardinals Prediction, the Rays are coming as -125 road favorites. Both teams were not far apart from each other last season and the Rays were struggling on the road, while the Cardinals were solid at home. Liberatore was better at home last season with a sub-4 ERA, while Rasmussen was slightly weaker on the road. The Rays were also weaker against lefties last season, with a .234 batting average against left-handed pitching, ranking just 21st in the league, so I don’t expect them to start the season with a road win. Take the Cardinals on the moneyline at home for plus money.

Nikos Lagouretos's Pick: St. Louis Cardinals ML

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