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Tampa Bay Rays vs San Diego Padres Prediction 4/25/25 MLB Picks

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San Diego Padres (17-8) vs Tampa Bay Rays (11-14)

Game Info: Friday, April 25, 2025 at 9:40 pm (Petco Park)

The Line: Betting Odds: San Diego Padres -142 / Tampa Bay Rays +120 — Over/Under: 7

(Get latest betting odds)

In this article, we will formulate a Rays vs Padres prediction for this MLB game on Friday, April 25, at PETCO Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays (11-14, 2-4 Away) spent four straight series at home and lost to the Angels, Red Sox, and Yankees, while they beat the Braves. The Rays opened their road series against the Diamondbacks with a loss, but bounced back with a pair of extra-inning wins. In the latest 7-4 victory last night,   Christopher Morel led the offense with three RBI, while Drew Rasmussen pitched for 5.0 innings in a no-decision, allowing four runs on five hits with five strikeouts and one walk. Edwin Uceta was credited with the win.

This year, the Rays average 4.36 runs per game (15th in the MLB) on a .255/.321/.397 triple-slash. When it comes to pitching, the Rays’ staff has a 3.75 ERA (9th) and 1.17 WHIP (8th). Jonathan Aranda leads the Rays with a .314 batting average, four home runs, and 13 RBI this season.

Shane Baz will take the mound for the Rays on Friday. The 25-year-old right-hander has a 2-0 record in four starts this year with a 3.22 ERA and 1.07 WHIP in 22.1 innings.

San Diego Padres Betting Preview

The San Diego Padres (17-8, 12-1 Home) returned home from two series on the road and losses to the Houston Astros and Detroit Tigers. For the first time this season, the Padres failed to score a single run in the latest 6-0 loss in Detroit. They registered just two hits, while Kyle Hart took the loss after allowing two runs on five hits with six strikeouts and one walk in 4.1 innings.

This year, the Padres average 4.12 runs per game (19th in the MLB) on a .263/.333/.401 triple-slash. When it comes to pitching, the Padres’ staff has a 2.92 ERA (2nd) and 1.12 WHIP (5th). Fernando Tatis Jr. leads the Padres with a .333 batting average, eight home runs, and 17 RBI this season.

The projected starting pitcher for the Padres is Michael King, who is 3-0 in five starts this season, with a 2.57 ERA and 1.07 WHIP in 28.0 innings.

Total Runs Facts

Matchup/League Facts

Rays vs Padres Prediction

The teams have traded wins in the past few years, as each recorded five in the previous ten H2H encounters. The Padres were better in four of the last five H2Hs. Shane Bazz struggled in his latest start against the Yankees, but other than that, he registered three quality starts this season. Michael King, on the other hand, didn’t allow more than three runs in a game, while he had a complete game shutout against the Rockies. I expect a low-scoring affair and a lot of strong defensive plays on each side. Seven of San Diego’s last ten games went Under. Go with Under.

Oliver Zivic's Pick: Under 7.5

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