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Tampa Bay Rays vs Houston Astros Prediction 5/29/25 MLB Picks

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Houston Astros (30-25) vs Tampa Bay Rays (28-27)

May 29, 2025 at 08:10 PM EDT

The Line: Betting Odds: Houston Astros -115 / Tampa Bay Rays -105 — Over/Under: 8

(Get latest betting odds)

The Tampa Bay Rays and Houston Astros meet Thursday in MLB action at Daikin Park. Here’s a Tampa Bay Rays vs Houston Astros Prediction. This article will include a Tampa Bay Rays vs Houston Astros Pick.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 28-27 on the year and play the Rangers, Marlins, and Red Sox next. The Tampa Bay Rays are batting .245 on the season, have a .309 OBP, and a .378 slugging percentage. The Tampa Bay Rays pitching staff has a 3.58 ERA and a 1.18 WHIP. Jonathan Aranda leads the Tampa Bay Rays with 52 hits and 30 RBI, while Junior Caminero and Yandy Diaz have combined for 97 hits and 55 RBI. 

Shane Baz gets the ball for the Tampa Bay Rays, and he is 4-3 with a 4.94 ERA and 52 strikeouts this season. Baz is 0-1 with a 3.65 ERA and 11 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 30-25 on the year and play the Pirates, Guardians, and White Sox next. The Houston Astros are batting .255 on the season, have a .324 OBP, and a .393 slugging percentage. The Houston Astros’ pitching staff has a 3.37 ERA and a 1.15 WHIP. Jeremy Pena leads the Houston Astros with 62 hits and 27 RBI, while Jose Altuve and Isaac Paredes have combined for 110 hits and 53 RBI.

Ryan Gusto gets the ball for the Houston Astros, and he is 3-2 with a 4.58 ERA and 38 strikeouts this season. This will be Gusto’s first career game against the Tampa Bay Rays.

Why the Houston Astros will win

  • The Rays have lost each of their last seven night games against the Astros at Daikin Park following a win.
  • The Astros have won each of their last eight Thursday games at Daikin Park.
  • The Astros have covered the run line in each of their last 10 Thursday night games.
  • The Rays have failed to cover the run line in each of their last six night games against AL West opponents.
  • The Rays have trailed after 5 innings in five of their last six night games against AL West opponents.
  • The Astros have led after 3 innings in four of their last five night games against American League opponents.

Why the Tampa Bay Rays will win

  • The Rays have won each of their last eight Thursday night road games.
  • The Astros have lost 15 of their last 22 games as favorites following a win.
  • The Rays have covered the run line in each of their last 13 Thursday games as underdogs against American League opponents.
  • The Astros have failed to cover the run line in five of their last six games as favorites against the Rays following a home win.
  • The Astros have trailed after 5 innings in six of their last eight games as favorites against American League opponents.

Houston Astros Player Prop Facts

  • Isaac Paredes has hit at least one home run in each of his last two appearances against former teams.
  • Christian Walker has recorded at least one Single in each of his last seven appearances with his team as a favorite against AL East opponents.
  • Jeremy Pena has scored at least one run in each of the Astros’ last five games against AL East opponents that held a winning record.
  • Mauricio Dubon has recorded at least one hit in each of his last 13 home appearances.
  • Brendan Rodgers has recorded at least one RBI in each of his last four appearances in night games against AL East teams that held a winning record.

Tampa Bay Rays Player Prop Facts

  • Josh Lowe has hit a home run in each of his last two appearances with the Rays as underdogs against AL West opponents.
  • Yandy Diaz has recorded a Double in three of the Rays’ last four games at Daikin Park against AL West opponents that held a winning record.
  • Brandon Lowe has recorded at least one RBI in four of his last five appearances with the Rays as underdogs against the Astros.
  • Brandon Lowe has scored at least one run in each of the Rays’ last seven games against AL opponents.
  • Yandy Diaz has recorded a Single in each of the Rays’ last five games against the Astros.
  • Brandon Lowe has recorded at least one hit in each of the Rays’ last 11 games.

Tampa Bay Rays vs Houston Astros Prediction

You can make a case for either the Rays or Astros, as they’ve both been on fire over the last week or so. However, I’m leaning toward the over in this contest. Baz has allowed 34 hits and 22 runs in his last 25.1 innings, and he has 13 walks to go with 16 strikeouts during that span. Gusto has allowed 13 hits and nine earned runs in his last 8.1 innings. In 29.2 home innings, Gusto has a 5.46 ERA and a .287 allowed batting average. These two pitchers are in rough shape, and they’re going up against hot offenses. I expect some fireworks. Give me the over between the Astros and Rays.

Randy Chambers's Pick: Over 8

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