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St. Louis Cardinals vs Tampa Bay Rays Prediction 8/24/2025 Today’s MLB Picks

Aug 22, 2025; St. Petersburg, Florida, USA; Tampa Bay Rays shortstop Carson Williams (77) celebrates after he hit a two-run home run during the seventh inning against the St. Louis Cardinals at George M. Steinbrenner Field. Mandatory Credit: Kim Klement Neitzel-Imagn Images

Aug 22, 2025; St. Petersburg, Florida, USA; Tampa Bay Rays shortstop Carson Williams (77) celebrates after he hit a two-run home run during the seventh inning against the St. Louis Cardinals at George M. Steinbrenner Field. Mandatory Credit: Kim Klement Neitzel-Imagn Images

MATCHUP St. Louis Cardinals Tampa Bay Rays
Team Records 64-67 63-67
Where George M. Steinbrenner Field, Tampa, Florida
When Sunday, August 24, 2025
Time 12:10 PM EDT
TV FanDuel SN MW

The St. Louis Cardinals and Tampa Bay Rays meet Sunday in MLB action at George M. Steinbrenner Field. Here’s a St. Louis Cardinals vs Tampa Bay Rays Prediction. This article will include a St. Louis Cardinals vs Tampa Bay Rays Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 64-66 on the year and play the Pirates, Reds, and Athletics next. The St. Louis Cardinals are batting .250 on the season, have a .318 OBP, and a .387 slugging percentage. The St. Louis Cardinals pitching staff has a 4.28 ERA and a 1.30 WHIP. Brendan Donovan leads the St. Louis Cardinals with 118 hits and 45 RBI, while Alec Burleson and Masyn Winn have combined for 232 hits and 105 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 6-10 with a 4.13 ERA and 93 strikeouts this season. This will be Liberatore’s second career game against the Tampa Bay Rays.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 62-67 on the year and play the Guardians, Nationals, and Mariners next. The Tampa Bay Rays are batting .251 on the season, have a .314 OBP, and a .400 slugging percentage. The Tampa Bay Rays pitching staff has a 4.03 ERA and a 1.22 WHIP. Yandy Diaz leads the Tampa Bay Rays with 135 hits and 73 RBI while Junior Caminero and Jonathan Aranda have combined for 236 hits and 141 RBI.

Ryan Pepiot gets the ball for the Tampa Bay Rays, and he is 8-10 with a 3.95 ERA and 146 strikeouts this season. This will be Pepiot’s first career game against the St. Louis Cardinals.

Why the Tampa Bay Rays will win

Why the St. Louis Cardinals will win

Tampa Bay Rays Player Prop Facts

St. Louis Cardinals Player Prop Facts

St. Louis Cardinals vs Tampa Bay Rays Prediction

I’m not excited to get behind either of these teams that have been shaky over the last few weeks. However, Pepiot has struggled this month, allowing 16 hits and 10 earned runs in his last 17.2 innings. Liberatore has a 3.73 ERA and .253 allowed batting average in 62.2 road innings, which is much better than his home splits. Also, Liberatore was drafted by the Rays in the first round of the 2018 draft, so there should be some motivation here for the 25-year-old. I’ll take a stab with the Cardinals on the road.

Randy Chambers's Pick: St. Louis Cardinals

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