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St. Louis Cardinals vs San Diego Padres Prediction 5/9/2026 Today’s MLB Picks

May 8, 2026; San Diego, California, USA; St. Louis Cardinals first baseman Alec Burleson (41) scores during the fifth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

May 8, 2026; San Diego, California, USA; St. Louis Cardinals first baseman Alec Burleson (41) scores during the fifth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP St. Louis Cardinals San Diego Padres
Team Records 23-15 22-16
Spread +1.5 -171 -1.5 141
Moneyline +123 -149
Total Over 8 (-108) Under 8 (-112)
Where Petco Park, San Diego, California
When Saturday, May 9, 2026
Time 07:15 PM EDT
TV MLB.TV
The St. Louis Cardinals and San Diego Padres meet Saturday in MLB action at Petco Park. Here’s a St. Louis Cardinals vs. San Diego Padres Prediction. This article will include a St. Louis Cardinals vs. San Diego Padres Pick.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 23-15 on the year and play the Athletics and Brewers next. The St. Louis Cardinals are batting .240 on the season and have a .324 OBP, and a .396 slugging percentage. The St. Louis Cardinals pitching staff has a 4.33 ERA and a 1.38 WHIP. Jordan Walker leads the St. Louis Cardinals with 42 hits and 27 RBI while Alec Burleson and Ivan Herrera have combined for 76 hits and 47 RBI.

Dustin May gets the ball for the St. Louis Cardinals, and he is 3-3 with a 5.15 ERA and 25 strikeouts this season. May is 2-4 with a 3.80 ERA and 53 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview


The San Diego Padres are 22-16 on the year and play the Brewers and Mariners next. The San Diego Padres are batting. 227 on the season, have a .299 OBP, and have a .373 slugging percentage. The San Diego Padres pitching staff has a 4.19 ERA and a 1.27 WHIP. Xander Bogaerts leads the San Diego Padres with 36 hits and 23 RBI, while Jackson Merrill and Fernando Tatis Jr. have combined for 67 hits and 31 RBI.

Randy Vasquez gets the ball for the San Diego Padres, and he is 3-1 with a 3.20 ERA and 36 strikeouts this season. Vasquez is 1-1 with a 4.91 ERA and 7 strikeouts in his career against the St. Louis Cardinals.

Why the San Diego Padres will win

Why the St. Louis Cardinals will win

Total Runs Facts

San Diego Padres Player Prop Facts

St. Louis Cardinals Player Prop Facts

Matchup/League Facts

St. Louis Cardinals vs San Diego Padres Prediction


The Padres have cooled off and their offense isn’t producing all of a sudden. The problem is May hasn’t been good through 36.2 innings with a 5.15 ERA and 1.53 WHIP. The Padres have also hit May well going back to his Dodgers days, as current hitters are batting. 263 with a .325 OBP in 76 at bats. If there was a game for the Padres’ bats to wake up, it’s this one. Vasquez has been solid through 39.1 innings with his 3.20 ERA and 1.17 WHIP. Give me the Padres for the win on Saturday night.

Randy Chambers's Pick: San Diego Padres

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