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St. Louis Cardinals vs Philadelphia Phillies Prediction 5/12/25 MLB Picks

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Philadelphia Phillies (24-16) vs St. Louis Cardinals (22-19)

Game Info: Monday, May 12, 2025 at 6:45 pm (Citizens Bank Park)

The Line: Betting Odds: Philadelphia Phillies -180 / St. Louis Cardinals +150 — Over/Under: 8

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The St. Louis Cardinals and the Philadelphia Phillies meet Monday in MLB action from Citizens Bank Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. Louis Cardinals vs. Philadelphia Phillies prediction.

Starting Pitching Matchup

The St. Louis Cardinals will send out Matthew Liberatore here, and Liberatore is 3-3 with a 3.07 ERA and 38 strikeouts this season. In his career, Liberatore is 1-0 with a 5.19 ERA and 10 strikeouts against Philadelphia. The Phillies will hand the ball to Cristopher Sanchez, and Sanchez is 4-1 with a 2.89 ERA and 44 strikeouts this season. In his career, Sanchez is 2-0 with a 2.19 ERA and 9 strikeouts against the Cardinals.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to add on to their 6-1 win over the Nationals to improve to their record to 22-19 on the year. After this series, the Cardinals will head on the road for a series against the Kansas City Royals.

Cardinals Win Eight In A Row

Brendan Donovan has a team-high 48 hits along with 12 doubles, 3 home runs, and 19 RBIs, while Lars Nootbaar has 26 hits with 4 home runs, 17 RBIs, and 3 stolen bases. Nolan Arenado also has 38 hits with 9 doubles, 6 home runs, and 22 RBIs of his own, and Victor Scott II has 36 hits with 6 doubles, a triple, 8 RBIs, and a team-high 11 stolen bases. Willson Contreras has also chipped in 38 hits with 6 home runs and 23 RBIs of his own this season.

Why the St. Louis Cardinals will win

St. Louis Cardinals Player Prop Facts

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to add on to their 3-0 win over the Guardians from Sunday’s series finale to improve to 24-16 on the year. After this series, the Phillies will square off against the Pittsburgh Pirates at home.

Phillies Win 7 Of Their Last 9

Nick Castellanos has 42 hits with 10 doubles, including 4 home runs and 21 RBI,s while Kyle Schwarber has 39 hits with a team-high 14 home runs and 32 RBIs as well on the year. Bryce Harper has 6 stolen bases, 7 home runs, and 22 RBIs. Trea Turner also has 48 hits with a team-high 9 stolen bases. Max Kepler has 8 doubles and Bryson Stott has 5 doubles, 2 triples, 3 homers, and 20 RBIs, while Stott also has 8 stolen bases this season.

Why the Philadelphia Phillies will win

Philadelphia Phillies Player Prop Facts

Total Runs Facts

St. Louis Cardinals vs. Philadelphia Phillies Prediction

I’m on the Phillies here. I get that the Cardinals have been playing well in their recent outings, but the thing here is that the Phillies are not the Nationals or the Pirates or anything. The Phillies have a strong lineup that’s been producing as of late, and Sanchez gives the Phillies a huge edge at starting pitcher, with how well Sanchez has come out of the gate so far this season. I’ll roll with the Phillies to draw first blood here.

Chris Ruffolo's Pick: Philadelphia Phillies -180

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