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St. Louis Cardinals vs Milwaukee Brewers Prediction 5/26/2026 Today’s MLB Picks

May 25, 2026; Milwaukee, Wisconsin, USA;  Milwaukee Brewers catcher William Contreras (24) slams his bat after hitting a fly ball during the seventh inning against the St. Louis Cardinals at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

May 25, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers catcher William Contreras (24) slams his bat after hitting a fly ball during the seventh inning against the St. Louis Cardinals at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

MATCHUP St. Louis Cardinals Milwaukee Brewers
Team Records 29-23 31-20
Spread +1.5 -148 -1.5 123
Moneyline +149 -181
Total Over 8 (-107) Under 8 (-113)
Where American Family Field, Milwaukee, Wisconsin
When Tuesday, May 26, 2026
Time 07:40 PM EDT
TV MLB.TV
The St. Louis Cardinals and Milwaukee Brewers meet Tuesday in MLB action at American Family Field. Here’s a St. Louis Cardinals vs Milwaukee Brewers Prediction. This article will include a St. Louis Cardinals vs Milwaukee Brewers Pick.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 29-23 on the year and play the Cubs and Rangers next. The St. Louis Cardinals are batting .239 on the season, with a .320 OBP and a .387 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.23 ERA and a 1.38 WHIP. Jordan Walker leads the St. Louis Cardinals with 58 hits and 42 RBI, while Alec Burleson and Ivan Herrera have combined for 108 hits and 61 RBI.

Michael McGreevy gets the ball for the St. Louis Cardinals, and he is 3-3 with a 2.40 ERA and 37 strikeouts this season. This will be McGreevy’s first career game against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview


The Milwaukee Brewers are 31-20 on the year and play the Giants and Astros next. The Milwaukee Brewers are batting. 248 on the season, have a .334 OBP, and have a .364 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.25 ERA and a 1.19 WHIP. William Contreras leads the Milwaukee Brewers with 58 hits and 31 RBI, while Brice Turang and Jake Bauers have combined for 96 hits and 59 RBI.

Kyle Harrison gets the ball for the Milwaukee Brewers, and he is 5-1 with a 1.77 ERA and 59 strikeouts this season. This will be Harrison’s first career game against the St. Louis Cardinals.

Why the Milwaukee Brewers will win

Why the St. Louis Cardinals will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

St. Louis Cardinals Player Prop Facts

Matchup/League Facts

St. Louis Cardinals vs Milwaukee Brewers Prediction


The Cardinals are ice cold offensively all of a sudden, and while McGreevy has been great, Harrison has been even better. Harrison has a 1.77 ERA and 1.07 WHIP through 45.2 innings. He has 59 strikeouts as well. In his last 22 innings, Harrison has allowed 18 hits and 3 runs. In 24.1 home innings, Harrison has a 1.85 ERA and a .211 allowed batting average. The Brewers are also hitting the ball better lately. Give me the Brewers at home.

Randy Chambers's Pick: Milwaukee Brewers

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