St. Louis Cardinals vs Miami Marlins Prediction 07/29/2025 Picks

The Miami Marlins and the St. Louis Cardinals meet Tuesday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Miami Marlins vs. St. Louis Cardinals prediction.

Starting Pitching Matchup

The Miami Marlins will send out Sandy Alcantara here and Alcantara is 5-9 with a 6.66 ERA and 77 strikeouts this season. In his last five starts against the Cardinals, Alcantara is 1-3 with a 1.93 ERA and 33 strikeouts. Sonny Gray will start for St. Louis and is 10-4 with a 4.33 ERA and 128 strikeouts this season. In his last five starts against the Marlins, Gray is 3-0 with a 1.42 ERA and 32 strikeouts.

Miami Marlins Recap

The Miami Marlins come into this game looking to rebound from a 7-1 loss at the hands of the Cardinals on Monday to sit at 50-55 on the year. After this series, the Marlins will head home for a series against the New York Yankees.

Marlins Drop Back-To-Back Games

Xavier Edwards has 105 hits including 17 doubles and a team-high 17 stolen bases while Eric Wagaman has 81 hits with 20 doubles. Otto Lopez has 82 hits with 14 doubles and 11 home runs with 54 RBIs. Kyle Stowers has 100 hits with 17 doubles, 3 triples, 23 home runs and 63 RBIs but also has 106 strikeouts so far this season. Agustin Ramirez also has 15 home runs, 23 doubles and 46 RBIs and Jesus Sanchez has chipped in 34 RBIs as well on the year.

Why the Miami Marlins will win

• The Cardinals have lost each of their last five games as favorites following a win.
• The Marlins have won each of their last five Tuesday games as underdogs.
• The Cardinals have failed to cover the run line in each of their last eight games as favorites following a home win.
• The Marlins have covered the run line in 14 of their last 16 road games against teams that held a winning record.

Miami Marlins Player Prop Facts

• Jesus Sanchez has hit a home run in two of the Marlins’ last three games against the Cardinals.
• Sandy Alcantara has recorded four or more strikeouts in each of his 18 previous appearances with the Marlins as underdogs against NL Central opponents.
• Otto Lopez has recorded at least one hit in each of his last 12 Tuesday appearances against teams that held a winning record.
• Kyle Stowers ranks 5th amongst qualified players for Slugging Percentage (.573) this season.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to build on their win over the Marlins from Monday’s matchup to improve to 55-53 this season. After this series, the Cardinals will head on the road for a series against the San Diego Padres.

Cardinals Looking To Build Some Momentum

Brendan Donovan has a team-high 110 hits along with 24 doubles, 9 home runs and 42 RBIs while Lars Nootbaar has 75 hits with 12 home runs, 37 RBIs, 15 doubles and 4 stolen bases. Nolan Arenado also has 83 hits with 15 doubles, 10 home runs and 43 RBIs of his own and Victor Scott II has 72 hits with 13 doubles, a triple, 33 RBIs and a team-high 27 stolen bases. Willson Contreras has also chipped in 97 hits with 28 doubles, 14 home runs and 61 RBIs of his own as well this season. Masyn Winn’s added 100 hits with 23 doubles, 7 home runs and 39 RBIs and Alec Burleson’s added 95 hits with 19 doubles, 14 home runs and 48 RBIs.

Why the St. Louis Cardinals will win

• The Marlins have lost six of their last seven games at Busch Stadium.
• The home team has won eight of the last 10 games between the Marlins and Cardinals.
• The Marlins have failed to cover the run line in nine of their last 10 games at Busch Stadium.
• The Cardinals have covered the run line in seven of their last eight games as home favorites against the Marlins.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in each of the Cardinals’ last two games as favorites.
• Willson Contreras has recorded a Double in three of the Cardinals’ last four games against opponents that held a losing record.
• Sonny Gray has recorded six or more strikeouts in seven of his last eight appearances in night games against NL teams that held a losing record.
• Masyn Winn has recorded at least one hit in each of the Cardinals’ last eight games against opponents that held a losing record.
• Sonny Gray has recorded a win in five of his last six appearances in night games.
• Sonny Gray is one of only five pitchers to record 90+ Strikeouts and 20 or less Walks this season.

Total Runs Facts

• Six of the Marlins’ last eight games against National League opponents have gone UNDER the total runs line.
• Three of the Cardinals’ last four games against NL East opponents have gone OVER the total runs line.

Miami Marlins vs. St. Louis Cardinals Prediction

I’m on the Marlins here. I get the case to be made for either side in this game, but the thing is that the Cardinals have had issues with offensive consistency. Sure, they looked good in Monday’s opener, but the Marlins aren’t that far off from the Cardinals in the standings, and a lot of the Marlins best work as of late has been done on the road. Sandy Alcantara has been getting rocked on the road this season with an ERA above 10, but I still think he’s a decent option that, like we saw in his last start, can put together a strong showing on any given night. I think the value here lies with Miami.