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St. Louis Cardinals vs Los Angeles Dodgers Prediction 08/06/2025 Today’s MLB Picks

Aug 5, 2025; Los Angeles, California, USA; Los Angeles Dodgers designated hitter Shohei Ohtani (17) looks on from the dugout during the ninth inning against the St. Louis Cardinals at Dodger Stadium. Mandatory Credit: William Liang-Imagn Images

Aug 5, 2025; Los Angeles, California, USA; Los Angeles Dodgers designated hitter Shohei Ohtani (17) looks on from the dugout during the ninth inning against the St. Louis Cardinals at Dodger Stadium. Mandatory Credit: William Liang-Imagn Images

MATCHUP St. Louis Cardinals Los Angeles Dodgers
Team Records 58-58 66-49
Where Dodger Stadium, Los Angeles, California
When Wednesday, August 6, 2025
Time 04:10 PM EDT
TV Sportsnet LA

In this article, we will formulate a Saint Louis Cardinals vs Los Angeles Dodgers Prediction for this MLB game on Wednesday, August 6th at the Dodger Stadium in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Dodgers Preview

The Los Angeles Dodgers have a 66-48 record this season and are sitting on the first place of the NL West. The Dodgers have a 36-22 home record and 56-55 in over/under. They are coming off a 12-6 home victory over the Cardinals, and are 5-3 in their last 8 games. Under is 10-1-1 in their last 12 games, and are playing the Blue Jays and the Angels next.

The Dodgers have a .255 batting average this season, .329 OBP and .441 slugging percentage. LA’s pitching staff has a 4.16 ERA and 1.31 WHIP.  Sohei Ohtani leads the Dodgers with 121 hits, in RBI, with 73 and in home runs, with 38. Will Smith is the team’s best hitter with a .321 batting average.

Shohei Ohtani (R) is the projected starting pitcher for the Dodgers, and he has a 0-0 record, 2.40 ERA and 1.27 WHIP.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 57-58 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 25-34 road record and are 58-51 in over/under They are coming off a 6-12 road defeat by the Dodgers, and are 3-7 in their last 10 games. Over is 3-1 in their last 4 games and are playing the Rockies and the Cubs next.

The Cardinals have a .249 batting average this season, .318 OBP and .388 Slugging percentage. Saint Louis’ pitching staff has a 4.24 ERA and 1.29 WHIP. Brendan Donovan leads the Cardinals with 113 hits, and he is the team’s best hitter with a .279 batting average. Wilson Contreras leads the team in RBI, with 64, adding a team-high 16 home runs.

Matthew Liberatore (R) is the projected starting pitcher for the Cardinals, and he has a 6-9 record, 3.96 ERA and 1.28 WHIP.

Why the Los Angeles Dodgers will win

Why the St. Louis Cardinals will win

Total Runs Facts

Matchup/League Facts

Saint Louis Cardinals vs Los Angeles Dodgers Prediction

The Cardinals are 3-2 in their 5 meetings against the Dodgers this season. Both teams are tied 2-2 wins in their last 4 meetings in Los Angeles, and under is 5-2 in their last 7 meetings.

In this Saint Louis Cardinals vs Los Angeles Dodgers Prediction, the Dodgers are coming as -210 home favorites. The Dodgers are rightfully favored, as they have a better overall record, and have been very strong at home, while Saint Louis has been terrible on the road. Liberatore has been better on the road for the Cardinals with a 3.52 road ERA, and he is coming off back-to-back quality starts with just one earned run in each. The Cardinals have a better bullpen, and the Dodgers have been weak against left-handed pitching, so I like the guests to keep this one close. Take the Saint Louis Cardinals by +1.5 runs in this one.

Nikos Lagouretos's Pick: Saint Louis Cardinals +1.5

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