| MATCHUP | St. Louis Cardinals | Houston Astros |
|---|---|---|
| Team Records | 13-8 | 8-15 |
| Where | Daikin Park, Houston, Texas | |
| When | Sunday, April 19, 2026 | |
| Time | 02:10 PM EDT | |
| TV | MLB.TV | |
The St. Louis Cardinals and Houston Astros meet Sunday in MLB action at Daikin Park. Here’s a St. Louis Cardinals vs. Houston Astros Prediction. This article will include a St. Louis Cardinals vs. Houston Astros Pick.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 12-8 on the year and play the Marlins and Mariners next. The St. Louis Cardinals are batting .234 on the season and have a .330 OBP, and a .385 slugging percentage. The St. Louis Cardinals pitching staff has a 4.90 ERA and a 1.43 WHIP. Jordan Walker leads the St. Louis Cardinals with 24 hits and 16 RBI while Alec Burleson and JJ Wetherholt have combined for 40 hits and 24 RBI.
Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 0-1 with a 4.29 ERA and 12 strikeouts this season. This will be Liberatore’s second career game against the Houston Astros.
Houston Astros Betting Preview
The Houston Astros are 8-14 on the year and play the Guardians and Yankees next. The Houston Astros are batting .257 on the season and have a .352 OBP, and a .431 slugging percentage. The Houston Astros pitching staff has a 6.19 ERA and a 1.65 WHIP. Yordan Alvarez leads the Houston Astros with 26 hits and 20 RBI, while Jose Altuve and Christian Walker have combined for 42 hits and 23 RBI.
Mike Burrows gets the ball for the Houston Astros, and he is 1-3 with a 6.55 ERA and 18 strikeouts this season. This will be Burrows’ first career game against the St. Louis Cardinals.
Why the Houston Astros will win
- The home team has won 16 of the Astros’ last 20 games.
- The Cardinals have lost four of their last five road games against AL West opponents following a road win.
- The Cardinals have failed to cover the run line in each of their last four day games against AL West opponents following a road win.
- The Astros have covered the run line in four of their last five day games against National League opponents that held a winning record.
- The Astros have led after 5 innings in six of their last seven day games against NL Central opponents that held a winning record.
Why the St. Louis Cardinals will win
- The Cardinals have won five of their last six games as underdogs against the Astros.
- The Astros have lost each of their last three games as favorites.
- The Astros have failed to cover the run line in eight of their last nine games against National League opponents.
- The Cardinals have covered the run line in each of their last four road games.
- The Astros have lost the first inning in each of their last three day games.
- The Cardinals have led after 5 innings in five of their last six games at Daikin Park.
- The Cardinals have led after 3 innings in five of their last six games at Daikin Park.
Total Runs Facts
- Each of the Cardinals’ last six games as underdogs against American League opponents has gone OVER the total runs line.
- Six of the Astros’ last seven day games against NL Central opponents have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last eight home games.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cardinals’ last six games against American League opponents.
Houston Astros Player Prop Facts
- Yainer Diaz has hit a home run in each of his three previous home appearances against the Cardinals.
- Yordan Alvarez has recorded at least one hit in each of the Astros’ last 11 games at Daikin Park.
- Yordan Alvarez ranks 1st amongst qualified players for Slugging Percentage (.789) this season.
St. Louis Cardinals Player Prop Facts
- Masyn Winn has hit a home run in each of his last two road appearances against the Astros after playing the previous day.
- Ramon Urias has recorded at least one hit in each of his last eight appearances in day games against AL West teams that held a losing record.
- Jordan Walker ranks 3rd amongst qualified players for Slugging Percentage (.662) this season.
Matchup/League Facts
- The Astros rank 30th in the league for walks allowed this season (120).
- The Astros rank 2nd in the league for on-base percentage this season (.352).
- The Cardinals rank T27th in the league for doubles this season (25).
- The Cardinals rank T27th in the league for triples this season (0).
St. Louis Cardinals vs Houston Astros Prediction
It’s a surprise to see the Cardinals as underdogs when you consider they’re playing the better baseball right now. The Astros are probably the better team on paper but they haven’t shown it this weekend. The Astros pitching staff also continues to stink to high heaven. Burrows has been one of those who has stunk up the joint. Maybe things turn around at some point but the Astros have the worst pitching staff in baseball right now. It’s awful. Give me the Cardinals and the more favorable price.