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St. Louis Cardinals vs Cincinnati Reds Prediction 5/24/2026 Today’s MLB Picks

May 23, 2026; Cincinnati, Ohio, USA;  A fireworks show is seen after the game between the St. Louis Cardinals and the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Aaron Doster-Imagn Images

May 23, 2026; Cincinnati, Ohio, USA; A fireworks show is seen after the game between the St. Louis Cardinals and the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Aaron Doster-Imagn Images

MATCHUP St. Louis Cardinals Cincinnati Reds
Team Records 29-22 27-25
Spread -1.5 147 +1.5 -178
Moneyline -101 -120
Total Over 9.5 (-114) Under 9.5 (-105)
Where Great American Ball Park, Cincinnati, Ohio
When Sunday, May 24, 2026
Time 01:40 PM EDT
TV MLB.TV
The St. Louis Cardinals and Cincinnati Reds meet Sunday in MLB action at Great American Ball Park. Here’s a St. Louis Cardinals vs. Cincinnati Reds Prediction. This article will include a St. Louis Cardinals vs. Cincinnati Reds Pick.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 29-22 on the year and play the Cubs and Brewers next. The St. Louis Cardinals are batting .242 on the season and have a .323 OBP, and a .393 slugging percentage. The St. Louis Cardinals pitching staff has a 4.20 ERA and a 1.37 WHIP. Jordan Walker leads the St. Louis Cardinals with 58 hits and 42 RBI while Alec Burleson and Ivan Herrera have combined for 108 hits and 60 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 2-2 with a 4.70 ERA and 43 strikeouts this season. Liberatore is 1-1 with a 3.32 ERA and 19 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview


The Cincinnati Reds are 27-25 on the year and play the Mets and Braves next. The Cincinnati Reds are batting. 227 on the season, have a .310 OBP, and have a .393 slugging percentage. The Cincinnati Reds pitching staff has a 4.78 ERA and a 1.47 WHIP. Elly De La Cruz leads the Cincinnati Reds with 60 hits and 35 RBI, while Sal Stewart and Spencer Steer have combined for 98 hits and 52 RBI.

Brady Singer gets the ball for the Cincinnati Reds, and he is 2-4 with a 6.26 ERA and 34 strikeouts this season. Singer is 2-3 with a 3.04 ERA and 29 strikeouts in his career against the St. Louis Cardinals.

Why the Cincinnati Reds will win

Why the St. Louis Cardinals will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

St. Louis Cardinals Player Prop Facts

Matchup/League Facts

St. Louis Cardinals vs Cincinnati Reds Prediction


Not a great pitching matchup, but the Cardinals are playing the better baseball and have the slightly better pitcher. Liberatore has a 4.70 ERA and 1.55 WHIP through 51.2 innings, while Singer has a 6.26 ERA and 1.70 WHIP through 46 innings. In his last 17 innings, Singer has allowed 26 hits and 16 runs. No, thanks. The Cardinals should have a field day in this spot. Give me the Cards.

Randy Chambers's Pick: St. Louis Cardinals

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