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St. Louis Cardinals vs Athletics Prediction 5/12/2026 Today’s MLB Picks

May 10, 2026; San Diego, California, USA; St. Louis Cardinals right fielder Jordan Walker (18) is congratulated by first baseman Alec Burleson (41) after hitting two-run home run during the fourth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

May 10, 2026; San Diego, California, USA; St. Louis Cardinals right fielder Jordan Walker (18) is congratulated by first baseman Alec Burleson (41) after hitting two-run home run during the fourth inning against the San Diego Padres at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP St. Louis Cardinals Oakland Athletics
Team Records 24-17 21-20
Spread +1.5 -156 -1.5 129
Moneyline +129 -156
Total Over 10 (-110) Under 10 (-110)
Where Sutter Health Park, Sacramento, California
When Tuesday, May 12, 2026
Time 09:40 PM EDT
TV ESPN Unlmtd
The St. Louis Cardinals and Athletics meet Tuesday in MLB action at Sutter Health Park. Here’s a St. Louis Cardinals vs. Athletics Prediction. This article will include a St. Louis Cardinals vs. Athletics Pick.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 23-17 on the year and play the Royals and Pirates next. The St. Louis Cardinals are batting .235 on the season and have a .318 OBP, and a .388 slugging percentage. The St. Louis Cardinals pitching staff has a 4.25 ERA and a 1.37 WHIP. Jordan Walker leads the St. Louis Cardinals with 44 hits and 29 RBI while Alec Burleson and Ivan Herrera have combined for 79 hits and 48 RBI.

Andre Pallante gets the ball for the St. Louis Cardinals, and he is 3-3 with a 4.34 ERA and 29 strikeouts this season. This will be Pallante’s first career game against the Athletics.

Athletics Betting Preview


The Athletics are 21-19 on the year and play the Giants and Angels next. The Athletics are batting. 249 on the season, have a .326 OBP, and have a .400 slugging percentage. The Athletics pitching staff has a 4.42 ERA and a 1.44 WHIP. Shea Langeliers leads the Athletics with 50 hits and 22 RBI while Jacob Wilson and Nick Kurtz have combined for 84 hits and 39 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 3-2 with a 3.89 ERA and 39 strikeouts this season. Springs is 0-2 with a 3.15 ERA and 14 strikeouts in his career against the St. Louis Cardinals.

Why the Athletics will win

Why the St. Louis Cardinals will win

Total Runs Facts

Athletics Player Prop Facts

St. Louis Cardinals Player Prop Facts

Matchup/League Facts

St. Louis Cardinals vs Athletics Prediction


The Athletics are playing better ball right now while the Cardinals’ bats have been quiet all week. The Athletics also have the edge on the mound in this match. Pallante has a 4.34 ERA and 1.37 WHIP through 37.1 innings, while Springs has a 3.89 ERA and 1.14 WHIP through 44 innings. The Athletics are finally starting to look like the fun surprise team they were expected to be before the season. A reasonable price, I’ll side with the A’s at home.

Randy Chambers's Pick: Athletics

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