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St. Louis Cardinals vs Arizona Diamondbacks Prediction 7/18/2026 Today’s MLB Picks

Jul 18, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks shortstop Blaze Alexander (9) turns a double play on St. Louis Cardinals second base Brendan Donovan (33) to tned the game in the ninth inning  at Chase Field. Mandatory Credit: Matt Kartozian-Imagn Images

Jul 18, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks shortstop Blaze Alexander (9) turns a double play on St. Louis Cardinals second base Brendan Donovan (33) to tned the game in the ninth inning at Chase Field. Mandatory Credit: Matt Kartozian-Imagn Images

MATCHUP St. Louis Cardinals Arizona Diamondbacks
Team Records 51-45 49-48
Spread -1.5 161 +1.5 -196
Moneyline +100 -120
Total Over 9 (-109) Under 9 (-111)
Where Chase Field, Phoenix, Arizona
When Saturday, July 18, 2026
Time 04:10 PM EDT
TV MLB.TV
The St. Louis Cardinals and Arizona Diamondbacks meet Saturday in MLB action at Chase Field. Here’s a St. Louis Cardinals vs Arizona Diamondbacks Prediction. This article will include a St. Louis Cardinals vs Arizona Diamondbacks Pick.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 51-45 on the year and play the Diamondbacks and Angels next. The St. Louis Cardinals are batting .242 on the season, with a .318 OBP and a .390 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.11 ERA and a 1.33 WHIP. Jordan Walker leads the St. Louis Cardinals with 106 hits and 74 RBI, while Alec Burleson and JJ Wetherholt have combined for 192 hits and 104 RBI.

Dustin May gets the ball for the St. Louis Cardinals, and he is 5-6 with a 4.55 ERA and 89 strikeouts this season. May is 2-2 with a 3.48 ERA and 27 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview


The Arizona Diamondbacks are 49-48 on the year and play the Cardinals and Athletics next. The Arizona Diamondbacks are batting. 237 on the season, have a .307 OBP, and have a .386 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.20 ERA and a 1.27 WHIP. Ketel Marte leads the Arizona Diamondbacks with 96 hits and 54 RBI, while Corbin Carroll and Geraldo Perdomo have combined for 166 hits and 81 RBI.

Brandon Pfaadt gets the ball for the Arizona Diamondbacks, and he is 3-1 with a 4.70 ERA and 41 strikeouts this season. Pfaadt is 1-0 with a 4.13 ERA and 19 strikeouts in his career against the St. Louis Cardinals.

Why the Arizona Diamondbacks will win

Why the St. Louis Cardinals will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

St. Louis Cardinals Player Prop Facts

St. Louis Cardinals vs Arizona Diamondbacks Prediction


I’m looking at the over in this spot. May has been hittable all season through 93 innings, as he has a 4.55 ERA and 1.26 WHIP. May has allowed 11 hits and 7 runs in his last 9.1 innings. In 36.1 innings on the road, May has a 5.94 ERA and a .284 allowed batting average. Pfaadt has a 4.70 ERA and 1.32 WHIP through 53.2 innings, and through 29 innings at home, he has a 5.28 ERA and a .243 allowed batting average. We saw some offense yesterday between these teams, and I expect more of the same here. Give me the over.

Randy Chambers's Pick: Over

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