Seattle Mariners vs Houston Astros Prediction 5/24/25 MLB Picks

The Seattle Mariners are visiting Houston Astros on Saturday, May 24th at the Daikin Park in the third game of this series, with both teams being tied 1-1 wins. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs Houston Astros Prediction. We will examine:

The Houston Astros recent form and player performance

The Seattle Mariners recent form and player performance

Recent betting trends and streaks involving the Houston Astros

Recent betting trends and streaks involving the Seattle Mariners

Recent betting trends in games played between the Seattle Mariners vs Houston Astros

A summary that ties it all together and produces a favorable betting outcome for A Seattle Mariners vs Houston Astros game

Houston Astros Preview

The Houston Astros have a 26-25 record this season and are sitting on the second place of the AL West. The Astros have a 16-10 home record and 21-28 in over/under. They are coming off a 3-5 home defeat by the Mariners, and are 1-3 in their last 4 games. Under is 8-3 in their last 11 games, and they are playing the Athletics and the Rays next.

The Astros have a .250 batting average this season, .320 OBP and .383 slugging percentage. Houston’s pitching staff has a 3.48 ERA and 1.16 WHIP. Jeremy Pena leads the Astros with 56 hits, while Isaac Paredes leads the team in RBI with 31, adding a team-high 11 home runs. Jake Meyers is the team’s best hitter, with a .309 batting average.

Framber Valdez (L) will take the mound for the Astros, and he has a 3-4 record, 3.57 ERA and 1.13 WHIP. He has been better at home with a 2.77 ERA across four home starts, and in his previous start against the Mariners this season, he had a shutout performance in 6 innings pitched. Framber Valdez is 6-3 with an ERA of 3.33 and 96 strikeouts in 17 appearances against the Mariners in his career.

Seattle Mariners Preview

The Seattle Mariners have a 29-21 record this season and are sitting on the first place of the AL West. The Mariners have a 16-10 road record and 27-21 in over/under They are coming off a 5-3 road victory over the Astros, and are 6-2 in their last 8 games. Under is 8-2 in their last 10 games and they are playing the Nationals and the Twins next.

The Mariners have a .237 batting average this season, .326 OBP and .402 Slugging percentage. Seattle’s pitching staff has a 3.72 ERA and 1.31 WHIP. Cal Raleigh leads the Mariners in hits with 47, in RBI with 35, and in home runs with 17. JP Crawford is the team’s best hitter with a .266 batting average.

Bryan Woo (R) will take the mound for the Mariners, and he has a 5-1 record, 2.65 ERA and 0.87 WHIP. He has been weaker on the road with a 3.52 ERA across six road starts, and he has been in excellent form with just one earned run in 13.1 innings pitched in his last two starts. Bryan Woo has a 1-0 record with an ERA of 2.31 and 9 strikeouts in 2 appearances against the Astros in his career.

Why the Houston Astros will win

• The Astros have won each of their last seven games at Daikin Park following a loss.
• The Mariners have lost each of their last four games against the Astros following a win.
• The Mariners have failed to cover the run line in each of their last four road games against AL West opponents following a win.
• The Astros have covered the run line in six of their last seven home games following a loss.
• The Astros have led after 5 innings in eight of their last nine day games against AL West opponents.
• The Astros have led after 3 innings in eight of their last nine day games against AL West opponents.

Why the Seattle Mariners will win

• The Mariners have won seven of their last eight games as road underdogs.
• The Astros have lost four of their last five games as favorites against the Mariners following a home loss.
• The Mariners have covered the run line in each of their last 10 games as underdogs against the Astros following a road win.
• The Astros have failed to cover the run line in each of their last eight games as favorites against the Mariners following a home loss.
• The Mariners have led after 3 innings in three of their last four day games against American League opponents that held a winning record.
• The Astros have trailed after 5 innings in six of their last seven games as home favorites against American League opponents.
• The Astros have lost the first inning in three of their last four home games against AL West opponents.

Total Runs Facts

• Each of the Mariners’ last six games as underdogs have gone UNDER the total runs line.
• Nine of the Astros’ last 10 day games against AL West opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last eight Saturday games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Mariners’ last five day games at Daikin Park.

Matchup/League Facts

• The Astros rank 2nd in the league for opponent batting average this season (.216).
• The Astros rank 28th in the league for steals this season (24).
• The Mariners rank 2nd in the league for walks this season (200).
• The Mariners are one of only three teams in the league to rank top 10 in both steals and home runs this season.

Seattle Mariners vs Houston Astros Prediction

The Mariners are 6-3 in their last 9 meetings against the Astros, and are 5-2 in their last 7 visits in Houston. In this Seattle Mariners vs Houston Astros Prediction, the Astros are coming as -120 home favorites. This should be closer to a pickem, as the Mariners have the better overall record, and the same number of road wins, as the Astros have at home. Both teams have top-10 bullpens with a combined 6.27 ERA, and both pitchers have also been sharp this season. Both teams are also 16-5 to the under in their last 21 games combined, so everything aligns for another low-scoring affair today. Take the under 7.5 runs.