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Seattle Mariners vs Houston Astros Prediction 07/20/2025 Picks

Jul 19, 2025; Seattle, Washington, USA;  Seattle Mariners shortstop J.P. Crawford (3) turns a double play after forcing out Houston Astros right fielder Cam Smith (11) at second base during the fifth inning at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images

Jul 19, 2025; Seattle, Washington, USA; Seattle Mariners shortstop J.P. Crawford (3) turns a double play after forcing out Houston Astros right fielder Cam Smith (11) at second base during the fifth inning at T-Mobile Park. Mandatory Credit: Stephen Brashear-Imagn Images

Houston (56-42) vs Seattle (53-45)

July 20, 2025 at 04:10 PM EDT

The Line: Betting Odds: Seattle -113 / Houston +102 — Over/Under: +6.5

(Get latest betting odds)

The Houston Astros are visiting the Seattle Mariners on Sunday, July 20th at the T-Mobile Park in the third game of this series, with the Mariners having a 2-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs Seattle Mariners Prediction. We will examine:

The Seattle Mariners’ recent form and player performance
The Houston Astros’ recent form and player performance
Recent betting trends and streaks involving the Seattle Mariners
Recent betting trends and streaks involving the Houston Astros
Recent betting trends in games played between the Houston Astros vs Seattle Mariners
A summary that ties it all together and produces a favorable betting outcome for the Houston Astros vs Seattle Mariners game

Seattle Mariners Preview

The Seattle Mariners have a 53-45 record this season and are sitting in second place in the AL West. The Mariners have a 27-21 home record and are 55-38 in over/under. They are coming off a 7-6 home victory over the Astros and have five consecutive wins. Over is 7-0 in their last 7 games, and they are playing the Brewers and the Angels next.

The Mariners have a .249 batting average this season, a .326 OBP, and a .416 Slugging percentage. Seattle’s pitching staff has a 3.86 ERA and 1.26 WHIP. J.P. Crawford leads the Mariners in hits with 101 and is the team’s best hitter with a .286 batting average. Cal Raleigh leads the team both in RBI with 83 and in home runs with 38.

Bryan Woo (R) is the projected starting pitcher for the Mariners, and he has an 8-4 record, 2.75 ERA, and 0.93 WHIP.

Houston Astros Preview

The Houston Astros have a 56-42 record this season and are sitting in first place in the AL West. The Astros have a 23-23 road record and are 43-51 in over/under. They are coming off a 6-7 road defeat by the Mariners, and are 1-7 in their last 8 games. Over is 8-4 in their last 12 games, and they are playing the Diamondbacks and the Athletics next.

The Astros have a .258 batting average this season, a .323 OBP, and a .407 slugging percentage. Houston’s pitching staff has a 3.64 ERA and 1.17 WHIP. Jeremy Pena leads the Astros with 102 hits, and he is the team’s best hitter, with a .322 batting average. Jose Altuve leads the team in RBI with 53, while Isaac Paredes adds a team-high 19 home runs.

Hunter Brown (R) is the projected starter for the Astros, and he has a 9-4 record, 2.43 ERA, and 0.96 WHIP.

Why the Seattle Mariners will win

The Mariners have won each of their last eight home games against AL West opponents.
The Astros have lost 11 of their last 12 games after going to extra innings.
The Mariners have covered the run line in each of their last eight day games against AL West opponents following a home win.
The Astros have failed to cover the run line in each of their last seven games after going to extra innings.
The Mariners have led after 5 innings in each of their last five games as favorites against American League opponents.
The Mariners have led after 3 innings in six of their last seven home games against AL West opponents.

Why the Houston Astros will win

The Astros have won each of their last eight day games against AL West opponents following a road loss.
The Mariners have lost three of their last four games as favorites against American League opponents following a home win.
The Astros have covered the run line in each of their last nine games as underdogs against American League opponents following a road loss.
The Mariners have failed to cover the run line in each of their last eight games following a home win.
The Mariners have lost the first inning in four of their last five day games against opponents that held a winning record.
The Mariners have trailed after 3 innings in three of their last four day games against American League opponents.
The Astros have led after 5 innings in three of their last four day games against the Mariners.

Total Runs Facts

Each of the Astros’ last six road games following an extra innings loss have gone UNDER the total runs line.
Each of the Mariners’ last six games after playing the previous day have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last 10 games at T-Mobile Park.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Mariners’ last nine day games at T-Mobile Park.

Matchup/League Facts

The Mariners rank 28th in the league for triples this season (5).
The Mariners are one of only three teams in the league to rank top 10 in both steals and home runs this season.
The Astros rank 1st in the league for strikeouts this season (948).
The Astros rank 1st in the league for opponent batting average this season (.225).

Houston Astros vs Seattle Mariners Prediction

The Mariners are 5-3 in their 8 meetings against the Astros this season, and are 4-1 in their last 5 meetings in Seattle. Under is 3-1 in their last 4 meetings.   

In this Houston Astros vs Seattle Mariners Prediction, the Mariners are coming as -125 home favorites. The Astros have a better record, but they are mediocre on the road. Both pitchers have been excellent, but Woo has been almost unhittable at home for the Mariners, with a 1.80 home ERA, and he has been in excellent form lately. Brown for the Astros has been struggling lately, with 10 earned runs in his last two starts, and the Astros have been terrible lately, while the Mariners have been red-hot. I expect the Mariners to keep rolling at home today, so take them on the moneyline.

Nikos Lagouretos's Pick: Seattle Mariners -113

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