San Francisco Giants vs Washington Nationals Prediction 5/24/25 MLB Picks

The San Francisco Giants and the Washington Nationals meet Saturday in MLB action from Nationals Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Washington Nationals prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Kyle Harrison for the start here and is 0-0 with a 3.38 ERA and 7 strikeouts this season. In his career, Harrison is 0-0 with a 4.22 ERA and 11 strikeouts against the Nationals. Washington will send out Jake Irvin for the start here and Irvin is 3-1 with a 3.88 ERA and 40 strikeouts this season. In his career, Irvin is 2-1 with a 4.00 ERA and 18 strikeouts against the Giants.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to build on their 4-0 win over the Nationals from Friday’s series opener to improve to 30-21 on the year. After this series, the Giants will head on the road for an interleague series against the Detroit Tigers.

Giants Still Trying To Find Consistency

Jung Hoo Lee has 53 hits including a team-high 14 doubles along with a pair of triples, 6 home runs and 31 RBIs with 3 stolen bases while Heliot Ramos has 55 hits with 11 doubles, 9 home runs and 26 RBIs. Wilmer Flores also has a team-high 10 home runs and 42 RBIs while Mike Yastrzemski has 5 home runs with 17 RBIs and 9 doubles and Matt Chapman and Tyler Fitzgerald each have a team-high 5 stolen bases as well on the year. Matt Chapman also has 38 hits with 9 home runs and 25 RBIs along with 7 doubles and Willy Adames has 42 hits with 10 doubles, 5 home runs and 23 RBIs.

Why the San Francisco Giants will win

• The Giants have won each of their last seven day games against teams that held a losing record.
• The Nationals have lost each of their last six games following a home loss.
• The Giants have covered the run line in each of their last six games against National League opponents.
• The Nationals have failed to cover the run line in each of their last five home games after playing the previous day.

San Francisco Giants Player Prop Facts

• Heliot Ramos has hit a home run in three of the Giants’ last four day games.
• Willy Adames has recorded a Double in four of the Giants’ last five games against NL opponents.
• Jung Hoo Lee has recorded an RBI in each of the Giants’ last four day games against NL teams that held a losing record.
• Heliot Ramos has scored at least one run in each of the Giants’ last seven games as road favorites against NL opponents.
• Heliot Ramos has recorded a Single in each of the Giants’ last eight games.
• Wilmer Flores has recorded at least one hit in each of his last 10 appearances against NL opponents.

Washington Nationals Recap

The Washington Nationals come into this game looking to bounce back after being shut out in their loss to the Giants on Friday, sitting at 23-28 on the year. After this series, the Nationals will head on the road for a series against the Seattle Mariners.

Nationals Have Five-Game Win Streak Snapped

Keibert Ruiz has 47 hits with 9 doubles and a pair of home runs with 20 RBIs while James Wood has 55 hits with 12 doubles and a team-high 12 home runs along with 33 RBIs and 7 stolen bases while also putting up 57 strikeouts. Nathaniel Lowe has 42 hits with 8 doubles and 34 RBIs along with 8 home runs and 57 strikeouts. CJ Abrams has 8 home runs and 19 RBIs along with 9 doubles and 9 stolen bases while Luis Garcia Jr. has 7 doubles and 7 stolen bases of his own this season. Dylan Crews has also logged a team-high 11 stolen bases as well this season.

Why the Washington Nationals will win

• The underdogs have won each of the Nationals’ last six games.
• The Giants have lost four of their last five games as road favorites.
• The underdogs have covered the run line in 14 of the Giants’ last 15 games.
• The Giants have failed to cover the run line in each of their last six games as favorites after playing the previous day.

Washington Nationals Player Prop Facts

• Keibert Ruiz has recorded a Double in each of the Nationals’ last three games as underdogs against NL opponents.
• Keibert Ruiz has recorded at least one RBI in each of the Nationals’ last four games as underdogs.
• Josh Bell has scored at least one run in five of his last six appearances in day games against NL West teams that held a winning record.
• Amed Rosario has recorded at least one Single in each of his last seven appearances with the Nationals as underdogs.
• CJ Abrams has recorded at least one hit in each of the Nationals’ last nine games as home underdogs against NL opponents.
• Paul DeJong has hit a home run in each of his last two appearances with his team as a home underdog against the Giants.

Total Runs Facts

• Eight of the Giants’ last nine day games against National League opponents have gone OVER the total runs line.
• Each of the Nationals’ last four day games against National League opponents have gone UNDER the total runs line.

San Francisco Giants vs. Washington Nationals Prediction

I’m back on the Nationals here. I don’t really know what to expect from Harrison in the start and the Nationals have been doing a good job of winning Jake Irvin’s starts as of late. Irvin also has a bloated ERA at home this season, but that’s from a couple of rough outings early on, and he has pitched a lot better at home in recent games. I’ll take my chances with the Nationals in this one.