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San Francisco Giants vs San Diego Padres Prediction 3/30/2026 Today’s MLB Picks

Mar 28, 2026; San Diego, California, USA; San Diego Padres right fielder Fernando Tatis Jr. (23) hits an RBI single during the third inning against the Detroit Tigers at Petco Park. Mandatory Credit: David Frerker-Imagn Images

Mar 28, 2026; San Diego, California, USA; San Diego Padres right fielder Fernando Tatis Jr. (23) hits an RBI single during the third inning against the Detroit Tigers at Petco Park. Mandatory Credit: David Frerker-Imagn Images

MATCHUP San Francisco Giants San Diego Padres
Team Records 0-3 1-2
Spread -1.5 151 +1.5 -183
Moneyline -102 -118
Total Over 8.5 (-101) Under 8.5 (-119)
Where Petco Park, San Diego, California
When Monday, March 30, 2026
Time 09:40 PM EDT
TV MLB.TV

The San Francisco Giants and the San Diego Padres meet Monday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. San Diego Padres prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Landen Roupp for the start here and Roupp was 7-7 with a 3.80 ERA and 102 strikeouts last season. In his career, Roupp is 0-2 with a 4.50 ERA and 15 strikeouts against the Padres. San Diego will send out Walker Buehler for the start and Buehler was 10-7 with a 4.93 ERA and 92 strikeouts last season. In his last five starts against the Giants, Buehler is 2-2 with a 3.21 ERA and 31 strikeouts.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to bounce back from their 3-1 loss at the hands of the New York Yankees last time out to sit at 0-3 this season. After this series, the Giants will head home for a series against the New York Mets.

Giants Still Searching For First Win

Rafael Devers, Luis Arraez and Heliot Ramos each have 3 hits with Devers and Ramos each logging a double while Matt Chapman has an RBI and Jung Hoo Lee has a double. Willy Adames and Harrison Bader each have a base knock as well this season.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their 3-0 win over Detroit last time out to improve to 1-2 this season. After this series, the San Diego Padres will head on the road for a series against the Boston Red Sox.

Padres Avoid Sweep Vs. Tigers

Xander Bogaerts has 3 hits with a double and an RBI while Ramon Laureano has 5 hits with a double, a home run and two RBIs. Jackson Merrill and Manny Machado each have a pair of hits with a double and Jake Cronenworth has 3 hits as well this season. Fernando Tatis Jr. also has a pair of base hits and an RBI as well this season.

San Francisco Giants @ San Diego Padres Betting Trends: March 30, 2026

Why the San Diego Padres will win

Why the San Francisco Giants will win

Total Runs Facts

San Diego Padres Player Prop Facts

San Francisco Giants Player Prop Facts

Matchup/League Facts

San Francisco Giants vs. San Diego Padres Prediction

I’m on the under here. I think that until we see either one of these teams break through offensively, the under has to be the look. San Francisco’s offense has been anemic through their first three games, and the Padres were kind of in the same boat through the first three games of the year and I think this one ends up being low-scoring so give me the under here.

Chris Ruffolo's Pick: Under 8.5

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