San Francisco Giants vs Milwaukee Brewers Prediction 6/1/2026 Today’s MLB Picks

The San Francisco Giants and the Milwaukee Brewers meet Monday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Milwaukee Brewers prediction.

Starting Pitching Matchup

The San Francisco Giants will send out Landen Roupp for the start here and Roupp is 5-5 with a 3.30 ERA and 68 strikeouts this season. In his career, Roupp is 0-1 with a 5.19 ERA and 5 strikeouts against the Brewers. Shane Drohan will start for Milwaukee and is 2-1 with a 2.63 ERA and 28 strikeouts this season. This will be Drohan’s first career start against the Giants.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to build on their 19-6 win over the Rockies from Sunday’s series finale to sit at 23-36 this season. After this series, the Giants will head on the road for a series against the Chicago Cubs.

Giants Snap Five-Game Slide

Luis Arraez has 70 hits with 10 doubles, 3 triples and 23 RBIs while Willy Adames has 57 hits with 17 doubles, 8 home runs and 23 RBIs along with 69 strikeouts. Matt Chapman has 51 hits with 15 doubles, a triple, a home run and 19 RBIs and Jung Hoo Lee has 59 hits with 12 doubles and 19 RBIs. Heliot Ramos has 44 hits with 12 doubles, 4 home runs and 20 RBIs this season. Rafael Devers also has 58 hits with 18 doubles, 7 home runs and 30 RBIs but also has 73 strikeouts this season.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to build on their 2-0 win over the Houston Astros last time out to sit at 35-21 this season. After this series, the Brewers will head on the road for a series against the Colorado Rockies.

Brewers Win 5 Of Last 6

William Contreras has 61 hits with 10 doubles, 4 home runs and 34 RBIs while Brice Turang’s added 51 hits with 11 doubles, a triple, 7 homers and 31 RBIs. Jake Bauers has 49 hits with 10 doubles, 9 home runs and 33 RBIs and Sal Frelick’s added 37 hits with 3 home runs and 18 RBIs this season. Luis Rengifo’s added 31 hits with 8 doubles and 14 RBIs and Garrett Mitchell has 34 hits wtih 9 doubles and 28 RBIs this season. 

San Francisco Giants @ Milwaukee Brewers Betting Trends: June 1, 2026

• Probable Starting Pitcher: Shane Drohan      Record this season: 2-1      ERA: 2.63
• Home Record: 1-0
• Last 5 against Giants: –

Why the Milwaukee Brewers will win

• The Giants have lost each of their last seven night games against National League opponents.
• The Brewers have won each of their last six night games against teams that held a losing record.
• The Giants have failed to cover the run line in each of their last seven night games against National League opponents.
• The Brewers have covered the run line in each of their last six Monday night home games against National League opponents.
• The Brewers have led after 3 innings in eight of their last nine games against NL West opponents.
• The Giants have lost the first inning in three of their last four games as road underdogs against National League opponents.
• The Brewers have led after 5 innings in eight of their last nine games as home favorites.

• Probable Starting Pitcher: Landen Roupp      Record this season: 5-5      ERA: 3.30
• Road Record: 3-2
• Last 5 against Brewers: 0-1

Why the San Francisco Giants will win

• The Giants have won each of their last four games as underdogs against NL Central opponents following a road win.
• The Brewers have lost five of their last six games against the Giants following a road win.
• The Giants have covered the run line in each of their last nine games as road underdogs against NL Central opponents.
• The Brewers have failed to cover the run line in each of their last six games against the Giants following a road win.
• The Brewers have trailed after 5 innings in three of their last four games.

Total Runs Facts

• Seven of the Brewers’ last eight games against National League opponents have gone UNDER the total runs line.
• Four of the Giants’ last five games as road underdogs have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last five games as underdogs against NL Central opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six games between the Giants and Brewers at American Family Field.

Milwaukee Brewers Player Prop Facts

• Jackson Chourio has hit a home run in three of his last four appearances in night games against NL West teams that held a losing record.
• William Contreras has recorded at least one hit in each of the Brewers’ last nine home games against opponents that held a losing record.

San Francisco Giants Player Prop Facts

• Casey Schmitt has hit a home run in three of the Giants’ last five games against opponents that held a winning record.
• Jung Hoo Lee has recorded at least one hit in each of his last 10 appearances against NL Central opponents that held a winning record.
• Luis Arraez ranks T2nd in the league in Hits (70) this season.

Matchup/League Facts

• The Brewers rank 30th in the league for home runs this season (40).
• The Brewers rank 1st in the league for home runs allowed this season (40).
• The Giants rank 1st in the league for doubles this season (121).
• The Giants rank 30th in the league for steals this season (15).

San Francisco Giants vs. Milwaukee Brewers Prediction

I’m on the Brewers in this one. I just feel like the Brewers are the better team in better form right now and while the Giants likely have an edge in starting pitching with Roupp over Drohan, but there’s not much else the Giants have going for them right now and I think that the Brewers keep their run going. Give me the Brewers.

Chris Ruffolo's Pick: Milwaukee -155