| MATCHUP | San Francisco Giants | Cincinnati Reds |
|---|---|---|
| Team Records | 7-12 | 11-8 |
| Where | Great American Ball Park, Cincinnati, Ohio | |
| When | Thursday, April 16, 2026 | |
| Time | 12:40 PM EDT | |
| TV | ESPN Unlmtd | |
The San Francisco Giants and Cincinnati Reds meet Thursday in MLB action at Great American Ball Park. Here’s a San Francisco Giants vs. Cincinnati Reds Prediction. This article will include a San Francisco Giants vs. Cincinnati Reds Pick.
San Francisco Giants Betting Preview
The San Francisco Giants are 6-12 on the year and play the Dodgers and Nationals next. The San Francisco Giants are batting. 243 on the season, have a .287 OBP, and have a .353 slugging percentage. The San Francisco Giants pitching staff has a 4.41 ERA and a 1.40 WHIP. Luis Arraez leads the San Francisco Giants with 21 hits and 6 RBI while Willy Adames and Matt Chapman have combined for 37 hits and 13 RBI.
Landen Roupp gets the ball for the San Francisco Giants, and he is 2-1 with a 3.24 ERA and 18 strikeouts this season. This will be Roupp’s second career game against the Cincinnati Reds.
Cincinnati Reds Betting Preview
The Cincinnati Reds are 11-7 on the year and play the Rays and Twins next. The Cincinnati Reds are batting. 207 on the season, have a .304 OBP, and have a .346 slugging percentage. The Cincinnati Reds pitching staff has a 3.81 ERA and a 1.36 WHIP. Elly De La Cruz leads the Cincinnati Reds with 20 hits and 11 RBI, while Sal Stewart and Eugenio Suarez have combined for 36 hits and 26 RBI.
Chase Burns gets the ball for the Cincinnati Reds, and he is 1-1 with a 3.31 ERA and 18 strikeouts this season. This will be Burns’ first career game against the San Francisco Giants.
Why the Cincinnati Reds will win
- The Reds have won nine of their last 10 day games against NL West opponents.
- The Giants have lost each of their last four road games.
- The Giants have failed to cover the run line in each of their last eight Thursday games.
- The Reds have covered the run line in five of their last six day games against NL West opponents following a win.
- The Reds have led after 3 innings in each of their last three games against NL West opponents.
- The Reds have led after 5 innings in four of their last five games as favorites.
Why the San Francisco Giants will win
- The Reds have lost four of their last five games as favorites against NL West opponents following a home win.
- The Giants have won each of their last five day games against the Reds following a loss.
- The Giants have covered the run line in each of their last eight games as road underdogs against NL Central opponents.
- The Reds have failed to cover the run line in seven of their last eight day games against the Giants following a win.
Total Runs Facts
- Each of the Reds’ last six home games after playing the previous day has gone OVER the total runs line.
- Eight of the Giants’ last nine day games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last eight games as favorites against National League opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Giants’ last 15 games as road underdogs against NL Central opponents.
Cincinnati Reds Player Prop Facts
- Elly De La Cruz has hit a home run in three of the Reds’ last four home games against opponents that held a losing record.
- Elly De La Cruz has recorded at least one hit in each of the Reds’ last eight home games.
- Sal Stewart ranks 2nd amongst qualified players for Slugging Percentage (.726) this season.
San Francisco Giants Player Prop Facts
- Matt Chapman has hit a home run in three of the Giants’ last five games as underdogs against the Reds.
- Willy Adames has recorded at least one hit in each of the Giants’ last seven games as underdogs.
- Landen Roupp ranks T9th in the league for Wins (2) this season.
Matchup/League Facts
- The Reds rank T28th in the league for hits this season (122).
- The Reds rank 27th in the league for runs scored this season (64).
- The Giants rank 30th in the league for steals this season (5).
- The Giants rank 30th in the league for walks this season (36).
San Francisco Giants vs Cincinnati Reds Prediction
Roupp has been solid through 16.2 frames, but it doesn’t matter when the Giants still can’t string together offense. This start to the season for the Giants has been frustrating. Burns is averaging more than a strikeout per inning and has been respectable through 16.1 innings, so this probably isn’t a spot where the Giants find their footing. Quick turnarounds also usually favor the home team. I have to ride with the Reds and continue to fade the Giants.