| MATCHUP | San Diego Padres | Washington Nationals |
|---|---|---|
| Team Records | 31-24 | 29-28 |
| Spread | -1.5 149 | +1.5 -181 |
| Moneyline | -102 | -119 |
| Total | Over 9 (-122) | Under 9 (102) |
| Where | Nationals Park, Washington, District of Columbia | |
| When | Friday, May 29, 2026 | |
| Time | 06:45 PM EDT | |
| TV | MLB.TV | |
The San Diego Padres and Washington Nationals meet Friday in MLB action at Nationals Park. Here’s a San Diego Padres vs Washington Nationals Prediction. This article will include a San Diego Padres vs Washington Nationals Pick.
San Diego Padres Betting Preview
The San Diego Padres are 31-24 on the year and play the Mets and Phillies next. The San Diego Padres are batting. 218 on the season, have a .291 OBP, and have a .361 slugging percentage. The San Diego Padres’ pitching staff has a 3.83 ERA and a 1.24 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 52 hits and 16 RBI, while Miguel Andujar and Xander Bogaerts have combined for 90 hits and 41 RBI.
Lucas Giolito gets the ball for the San Diego Padres, and he is 2-0 with a 2.70 ERA and 5 strikeouts this season. This will be Giolito’s second career game against the Washington Nationals.
Washington Nationals Betting Preview
The Washington Nationals are 29-28 on the year and play the Marlins and Diamondbacks next. The Washington Nationals are batting .245 on the season and have a .324 OBP and a .420 slugging percentage. The Washington Nationals pitching staff has a 4.64 ERA and a 1.38 WHIP. CJ Abrams leads the Washington Nationals with 60 hits and 47 RBI, while James Wood and Daylen Lile have combined for 118 hits and 64 RBI.
Paxton Schultz gets the ball for the Washington Nationals, and he is 0-2 with a 5.30 ERA and 21 strikeouts this season. This will be Schultz’s first career game against the San Diego Padres.
Why the Washington Nationals will win
- The Nationals have won five of their last six games as underdogs against National League opponents following a road loss.
- The Padres have lost five of their last seven games as favorites against National League opponents.
- The Nationals have covered the run line in each of their last nine games as underdogs.
- The Padres have failed to cover the run line in each of their last four games against National League opponents.
- The Padres have trailed after 3 innings in three of their last four games.
- The Padres have trailed after 5 innings in each of their last three road games against opponents that held a winning record.
Why the San Diego Padres will win
- The Padres have won each of their last seven road games against National League opponents following a loss.
- The Nationals have lost each of their last seven Friday games against NL West opponents that held a winning record.
- The Padres have covered the run line in each of their last eight road games against the Nationals following a loss.
- The Nationals have failed to cover the run line in eight of their last nine games as home underdogs against National League opponents following a road loss.
- The Nationals have trailed after 3 innings in 10 of their last 11 Friday games as home underdogs.
- The Nationals have trailed after 5 innings in three of their last four games at Nationals Park against NL West opponents that held a winning record.
Total Runs Facts
- Each of the Nationals’ last six night games against National League opponents has gone OVER the total runs line.
- Nine of the Padres’ last 10 games as favorites have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last four games as underdogs against National League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last four night games against National League opponents.
Washington Nationals Player Prop Facts
- CJ Abrams has hit a home run in three of the Nationals’ last four night games.
- Keibert Ruiz has recorded two or more hits in four of his last five home appearances.
- James Wood ranks 3rd amongst qualified players for On Base Percentage (.414) this season.
San Diego Padres Player Prop Facts
- Lucas Giolito has recorded four or more strikeouts in eight of his last nine appearances with his team as a favorite.
- Xander Bogaerts has recorded at least one hit in 16 of his last 17 road appearances against NL East opponents that held a winning record.
- Luis Campusano has hit a home run in three of his last four appearances with the Padres as favorites against NL opponents.
Matchup/League Facts
- The Nationals rank 30th in the league for runs allowed this season (310).
- The Nationals rank 2nd in the league for RBIs this season (288).
- The Padres rank 30th in the league for on-base percentage this season (.291).
- The Padres rank 29th in the league for slugging percentage this season (.361).
San Diego Padres vs Washington Nationals Prediction
I’m not a believer that the Nationals will keep up their recent winning ways. The Padres are also a super talented team that’s due for a victory. While both of these pitchers have small sample sizes, it’s Giolito who is more trustworthy, given he’s been an All-Star, while Schultz will make just his third career start. We’re getting a pick-em price. I’ll gladly side with the Padres in this spot.

