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San Diego Padres vs Washington Nationals Prediction 5/29/2026 Today’s MLB Picks

May 27, 2026; San Diego, California, USA; San Diego Padres shortstop Xander Bogaerts (2) throws over Philadelphia Phillies third baseman Alec Bohm (28) as he turns a double play during the second inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

May 27, 2026; San Diego, California, USA; San Diego Padres shortstop Xander Bogaerts (2) throws over Philadelphia Phillies third baseman Alec Bohm (28) as he turns a double play during the second inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP San Diego Padres Washington Nationals
Team Records 31-24 29-28
Spread -1.5 149 +1.5 -181
Moneyline -102 -119
Total Over 9 (-122) Under 9 (102)
Where Nationals Park, Washington, District of Columbia
When Friday, May 29, 2026
Time 06:45 PM EDT
TV MLB.TV

The San Diego Padres and Washington Nationals meet Friday in MLB action at Nationals Park. Here’s a San Diego Padres vs Washington Nationals Prediction. This article will include a San Diego Padres vs Washington Nationals Pick.

San Diego Padres Betting Preview

The San Diego Padres are 31-24 on the year and play the Mets and Phillies next. The San Diego Padres are batting. 218 on the season, have a .291 OBP, and have a .361 slugging percentage. The San Diego Padres’ pitching staff has a 3.83 ERA and a 1.24 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 52 hits and 16 RBI, while Miguel Andujar and Xander Bogaerts have combined for 90 hits and 41 RBI.

Lucas Giolito gets the ball for the San Diego Padres, and he is 2-0 with a 2.70 ERA and 5 strikeouts this season. This will be Giolito’s second career game against the Washington Nationals.

Washington Nationals Betting Preview

The Washington Nationals are 29-28 on the year and play the Marlins and Diamondbacks next. The Washington Nationals are batting .245 on the season and have a .324 OBP and a .420 slugging percentage. The Washington Nationals pitching staff has a 4.64 ERA and a 1.38 WHIP. CJ Abrams leads the Washington Nationals with 60 hits and 47 RBI, while James Wood and Daylen Lile have combined for 118 hits and 64 RBI.

Paxton Schultz gets the ball for the Washington Nationals, and he is 0-2 with a 5.30 ERA and 21 strikeouts this season. This will be Schultz’s first career game against the San Diego Padres.

Why the Washington Nationals will win

Why the San Diego Padres will win

Total Runs Facts

Washington Nationals Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

San Diego Padres vs Washington Nationals Prediction

I’m not a believer that the Nationals will keep up their recent winning ways. The Padres are also a super talented team that’s due for a victory. While both of these pitchers have small sample sizes, it’s Giolito who is more trustworthy, given he’s been an All-Star, while Schultz will make just his third career start. We’re getting a pick-em price. I’ll gladly side with the Padres in this spot.

Randy Chambers's Pick: San Diego Padres

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