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San Diego Padres vs Toronto Blue Jays Prediction 5/20/25 MLB Picks

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Toronto Blue Jays (22-24) vs San Diego Padres (27-18)

Game Info: Tuesday, May 20, 2025 at 7:07 pm (Rogers Centre)

The Line: Betting Odds: Toronto Blue Jays / San Diego Padres — Over/Under:

(Get latest betting odds)

The San Diego Padres and Toronto Blue Jays meet Tuesday in MLB action at Rogers Centre. Here’s a San Diego Padres vs Toronto Blue Jays Prediction. This article will include a San Diego Padres vs Toronto Blue Jays Pick.

San Diego Padres Betting Preview

The San Diego Padres are 27-18 on the year and play the Braves, Marlins, and Pirates next. The San Diego Padres are batting .261 on the season, have a .328 OBP, and a .396 slugging percentage. The San Diego Padres pitching staff has a 3.39 ERA and a 1.17 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 52 hits and 27 RBI, while Manny Machado and Luis Arraez have combined for 99 hits and 35 RBI. 

Dylan Cease gets the ball for the San Diego Padres, and he is 1-2 with a 4.60 ERA and 58 strikeouts this season. Cease is 1-0 with a 0.69 ERA and 18 strikeouts in his career against the Toronto Blue Jays.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 22-24 on the year and play the Rays, Rangers, and Athletics next. The Toronto Blue Jays are batting .249 on the season, have a .318 OBP, and a .380 slugging percentage. The Toronto Blue Jays pitching staff has a 4.31 ERA and a 1.25 WHIP. Bo Bichette leads the Toronto Blue Jays with 57 hits and 22 RBI, while Vladimir Guerrero Jr. and Alejandro Kirk have combined for 88 hits and 38 RBI.

Chris Bassitt gets the ball for the Toronto Blue Jays, and he is 3-2 with a 3.16 ERA and 55 strikeouts this season. Bassitt is 1-3 with a 4.44 ERA and 32 strikeouts in his career against the San Diego Padres.

Why the Toronto Blue Jays will win

Why the San Diego Padres will win

Toronto Blue Jays Player Prop Facts

San Diego Padres Player Prop Facts

San Diego Padres vs Toronto Blue Jays Prediction

The Padres are the better team, and they’re due for a breakout performance offensively, but they’ve scored a combined three runs in their last three games. Cease has been better lately, but he’s been hittable this season overall with a 4.60 ERA and 1.34 WHIP. In 19.2 innings, Cease has a 6.41 ERA and a .253 allowed batting average. Bassitt has simply been the better pitcher this season with his 3.16 ERA and 1.27 WHIP, and he has a 2.05 ERA in 22 home innings. We’re getting the Blue Jays at home with the better starting pitching option, while the Padres are in a funk offensively. Give me the Blue Jays.

Randy Chambers's Pick: Toronto Blue Jays

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