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San Diego Padres vs Seattle Mariners Prediction 5/15/2026 Today’s MLB Picks

May 14, 2026; Houston, Texas, USA; Seattle Mariners catcher Mitch Garver (18) is unable to catch a foul ball hit by Houston Astros second baseman Jose Altuve (not shown) during the seventh inning at Daikin Park. Mandatory Credit: Erik Williams-Imagn Images

May 14, 2026; Houston, Texas, USA; Seattle Mariners catcher Mitch Garver (18) is unable to catch a foul ball hit by Houston Astros second baseman Jose Altuve (not shown) during the seventh inning at Daikin Park. Mandatory Credit: Erik Williams-Imagn Images

MATCHUP San Diego Padres Seattle Mariners
Team Records 25-18 22-23
Spread +1.5 -181 -1.5 149
Moneyline +113 -136
Total Over 7 (-117) Under 7 (-103)
Where T-Mobile Park, Seattle, Washington
When Friday, May 15, 2026
Time 09:40 PM EDT
TV MLB.TV
The San Diego Padres and Seattle Mariners meet Friday in MLB action at T-Mobile Park. Here’s a San Diego Padres vs. Seattle Mariners Prediction. This article will include a San Diego Padres vs. Seattle Mariners Pick.

San Diego Padres Betting Preview


The San Diego Padres are 25-18 on the year and play the Dodgers and Athletics next. The San Diego Padres are batting. 222 on the season, have a .294 OBP, and have a .365 slugging percentage. The San Diego Padres pitching staff has a 4.14 ERA and a 1.26 WHIP. Xander Bogaerts leads the San Diego Padres with 39 hits and 23 RBI, while Jackson Merrill and Fernando Tatis Jr. have combined for 72 hits and 33 RBI.

Randy Vasquez gets the ball for the San Diego Padres, and he is 4-1 with a 3.05 ERA and 42 strikeouts this season. This will be Vasquez’s second career game against the Seattle Mariners.

Seattle Mariners Betting Preview


The Seattle Mariners are 22-23 on the year and play the White Sox and Royals next. The Seattle Mariners are batting. 232 on the season, have a .322 OBP, and have a .386 slugging percentage. The Seattle Mariners’ pitching staff has a 3.62 ERA and a 1.23 WHIP. Randy Arozarena leads the Seattle Mariners with 49 hits and 16 RBI while Josh Naylor and Julio Rodriguez have combined for 88 hits and 40 RBI.

Emerson Hancock gets the ball for the Seattle Mariners, and he is 3-1 with a 3.21 ERA and 50 strikeouts this season. Hancock is 0-0 with a 2.30 ERA and 12 strikeouts in his career against the San Diego Padres.

Why the Seattle Mariners will win

Why the San Diego Padres will win

Total Runs Facts

Seattle Mariners Player Prop Facts

San Diego Padres Player Prop Facts

Matchup/League Facts

San Diego Padres vs Seattle Mariners Prediction


This should be a fun game between two contenders out west and both Vasquez and Hancock are having strong seasons. I’m rolling with the Mariners at home, as they’ve played some of their better baseball over the last week or so and Hancock has been even better at home through 23 innings, where he has a 2.74 ERA and .210 allowed batting average. I like the direction the Mariners are heading, as they’re slowly but surely looking like the WS contender we expected to see from the start. Give me the Mariners.

Randy Chambers's Pick: Seattle Mariners

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