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San Diego Padres vs San Francisco Giants Prediction 8/13/2025 Today’s MLB Picks

Aug 12, 2025; San Francisco, California, USA; San Francisco Giants second baseman Casey Schmitt (10) hits a single against the San Diego Padres during the fifth inning at Oracle Park. Mandatory Credit: Robert Edwards-Imagn Images

Aug 12, 2025; San Francisco, California, USA; San Francisco Giants second baseman Casey Schmitt (10) hits a single against the San Diego Padres during the fifth inning at Oracle Park. Mandatory Credit: Robert Edwards-Imagn Images

MATCHUP San Diego Padres San Francisco Giants
Team Records 69-52 59-61
Where Oracle Park, San Francisco, California
When Wednesday, August 13, 2025
Time 03:45 PM EDT
TV Padres.TV

The San Diego Padres and the San Francisco Giants meet Wednesday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. San Francisco Giants prediction.

Starting Pitching Matchup

The San Diego Padres will send out Nick Pivetta for the start here and Pivetta is 11-4 with a 2.94 ERA and 139 strikeouts this season. In his career, Pivetta is 2-1 with a 4.87 ERA and 24 strikeouts. San Francisco will trot out Kai-Wei Teng for the start here and Teng is 1-1 with a 5.40 ERA and 8 strikeouts this season. This will be Teng’s first career start against the Padres.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their 5-1 win over the San Francisco Giants last time out to sit at 68-52 on the year. After this series, the Padres will welcome the Los Angeles Dodgers to town for an interleague series.

Padres Win 4 Straight and 7 Of Last 9

Manny Machado has 137 hits including a team-high 29 doubles, 20 home runs, 72 RBIs and 11 stolen bases while Fernando Tatis Jr. has 118 hits with 17 home runs and 46 RBIs along with 24 stolen bases of his own this season. Luis Arraez has added 135 hits with 23 doubles, 4 triples, 6 home runs and 44 RBIs while Jackson Merrill’s added 88 hits with 9 home runs and 51 RBIs as well. Xander Bogaerts also has 26 doubles and 19 stolen bases as well this season. Gavin Sheets also has 16 doubles, 15 home runs and 54 RBIs as well this season.

Why the San Diego Padres will win

San Diego Padres Player Prop Facts

San Francisco Giants Recap

The San Francisco Giants will be looking to rebound from their 5-1 loss at the hands of the Padres on Tuesday to sit at 59-61 this season. After this series, the Rays will pay a visit to Oracle Park to duke it out with the Rays.

Giants Drop 4th In a Row

Jung Hoo Lee has 110 hits including a team-high 27 doubles along with 9 triples, 6 home runs and 46 RBIs with 8 stolen bases while Heliot Ramos has 120 hits with 20 doubles, 14 home runs and 51 RBIs. Wilmer Flores also 12 home runs and 59 RBIs while Tyler Fitzgerald has a team-high 9 stolen bases as well on the year. Matt Chapman also has 79 hits with 16 home runs and 44 RBIs along with 15 doubles and Willy Adames has 100 hits with 18 doubles, 18 home runs and 61 RBIs of his own this season.

Why the San Francisco Giants will win

San Francisco Giants Player Prop Facts

Total Runs Facts

San Diego Padres vs. San Francisco Giants Prediction

I’m on the Padres here. I just like what I’ve seen from San Diego in certain games, and I think that Nick Pivetta gives the Padres a clear and decisive edge in starting pitching and it was San Diego that went out and incredibly beefed up their lineup and starting rotation. Give me San Diego here.

Chris Ruffolo's Pick: San Diego -160

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