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San Diego Padres vs San Francisco Giants Prediction 8/11/2025 Today’s MLB Picks

Aug 10, 2025; San Francisco, California, USA; San Francisco Giants first baseman Rafael Devers (16) walks to the dugout after grounding out against the Washington Nationals during the ninth inning at Oracle Park. Mandatory Credit: Darren Yamashita-Imagn Images

Aug 10, 2025; San Francisco, California, USA; San Francisco Giants first baseman Rafael Devers (16) walks to the dugout after grounding out against the Washington Nationals during the ninth inning at Oracle Park. Mandatory Credit: Darren Yamashita-Imagn Images

MATCHUP San Diego Padres San Francisco Giants
Team Records 67-52 59-60
Where Oracle Park, San Francisco, California
When Monday, August 11, 2025
Time 09:45 PM EDT
TV Padres.TV

The San Diego Padres and San Francisco Giants meet Monday in MLB action at Oracle Park. Here’s a San Diego Padres vs San Francisco Giants Prediction. This article will include a San Diego Padres vs San Francisco Giants Pick.

San Diego Padres Betting Preview

The San Diego Padres are 66-52 on the year and play the Dodgers, Giants, and Dodgers next. The San Diego Padres are batting .251 on the season, have a .321 OBP, and a .380 slugging percentage. The San Diego Padres pitching staff has a 3.62 ERA and a 1.22 WHIP. Luis Arraez leads the San Diego Padres with 135 hits and 44 RBI, while Manny Machado and Fernando Tatis Jr. have combined for 250 hits and 118 RBI. 

Yu Darvish gets the ball for the San Diego Padres, and he is 1-3 with a 6.51 ERA and 23 strikeouts this season. Darvish is 2-3 with a 5.89 ERA and 78 strikeouts in his career against the San Francisco Giants.

San Francisco Giants Betting Preview

The San Francisco Giants are 59-59 on the year and play the Rays, Padres, and Brewers next. The San Francisco Giants are batting .233 on the season, have a .311 OBP, and a .376 slugging percentage. The San Francisco Giants pitching staff has a 3.64 ERA and a 1.28 WHIP. Heliot Ramos leads the San Francisco Giants with 123 hits and 51 RBI while Jung Hoo Lee and Willy Adames have combined for 208 hits and 107 RBI.

Logan Webb gets the ball for the San Francisco Giants, and he is 10-8 with a 3.24 ERA and 165 strikeouts this season. Webb is 4-4 with a 2.98 ERA and 78 strikeouts in his career against the San Diego Padres.

Why the San Francisco Giants will win

Why the San Diego Padres will win

San Francisco Giants Player Prop Facts

San Diego Padres Player Prop Facts

San Diego Padres vs San Francisco Giants Prediction

We know what Darvish is capable of when he’s right, but he’s had issues working his way back into form. In 27.2 innings this season, Darvish has allowed 26 hits and 20 runs. Darvish has also walked 11 in those frames, so control has been an issue as well. Webb has not only been solid this season, but he’s been fantastic at Oracle in his career. In 80 career starts in San Francisco, Webb has a 2.78 ERA and 1.12 WHIP. The Giants have been a mess in the second half, but with a clear edge on the mound, I’ll back them in this spot.

Randy Chambers's Pick: San Francisco Giants

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