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San Diego Padres vs New York Mets Prediction 07/29/2025 Picks

Jul 28, 2025; San Diego, California, USA; San Diego Padres right fielder Fernando Tatis Jr. (23) makes a catch on a ball hit by New York Mets third baseman Ronny Mauricio (10) during the sixth inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

Jul 28, 2025; San Diego, California, USA; San Diego Padres right fielder Fernando Tatis Jr. (23) makes a catch on a ball hit by New York Mets third baseman Ronny Mauricio (10) during the sixth inning at Petco Park. Mandatory Credit: Denis Poroy-Imagn Images

MATCHUP New York Mets San Diego Padres
Team Records 62-47 60-49
Where Petco Park, San Diego, California
When Tuesday, July 29, 2025
Time 09:40 PM EDT
TV MLBN

In this article, we will formulate a New York Mets vs San Diego Padres Prediction for this MLB game on Tuesday, July 29th at the Petco Park in the second game of this series, with the Padres having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Preview

The San Diego Padres have a 58-49 record this season and are sitting on the second place of the NL West. They have a 32-18 home record, and are 44-60 in over/under. The Padres are coming off a 7-6 home victory over the Mets, and have three consecutive wins. Under is 5-3 in their last 8 games and are playing the Cardinals and the Diamondbacks next. 

The Padres have a .250 batting average this season, .317 OBP and .379 Slugging percentage. San Diego’s pitching staff has a 3.60 ERA and 1.23 WHIP.  Manny Machado leads the Padres with 124 hits, adding team-high .302 batting average and a team-high 66 RBI. He also adds a team-high 19 home runs. 

Ryan Bergert (R) will take the mound for the Padres, and he has a 1-0 record, 2.84 ERA and 1.14 WHIP.

New York Mets Preview

The New York Mets have a 62-45 record this season and are sitting on the first place of the NL East. The Mets have a 25-29 road record and are 47-55 in over/under. They are coming off a 6-7 road defeat by the Padres, which snapped their previous seven-game winning streak. They are playing the Giants and the Guardians next.

The Mets have a .243 batting average this season, .322 OBP and .414 slugging percentage. New York’s pitching staff has a 3.54 ERA and 1.31 WHIP.  Pete Alonso leads the Mets with 107 hits, adding a team-high 81 RBI and leads the team in batting average with .263. Juan Soto adds team-high 25 home runs.

Sean Manaea (L) will take the mound for the Mets, and he has a 1-1 record, 2.19 ERA and 0.97 WHIP.

Why the San Diego Padres will win

Why the New York Mets will win

Total Runs Facts

Matchup/League Facts

New York Mets vs San Diego Padres Prediction

The Mets are 5-3 in their last 8 overall meetings against the Padres, but the Padres are 5-2 in their last 7 meetings in San Diego. Over is 4-2 in their last 6 meetings. 

In this New York Mets vs San Diego Padres Prediction, the Mets are coming as -125 road favorites. The Mets have a better overall record, but they have been below average on the road, while the Padres are one of the best home teams in the league. Manaea has been excellent in his two starts this season, and the Padres struggle against lefties, so I like the New York Mets to bounce back on the road and even the series today.

Nikos Lagouretos's Pick: New York Mets -106

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