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San Diego Padres vs Milwaukee Brewers Prediction 6/7/25 MLB Picks

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Milwaukee Brewers (34-30) vs San Diego Padres (36-26)

Game Info: Saturday, June 7, 2025 at 7:35 pm (American Family Field)

The Line: Betting Odds: Milwaukee Brewers -115 / San Diego Padres -105 — Over/Under: 8.5

(Get latest betting odds)

The San Diego Padres and Milwaukee Brewers meet Saturday in MLB action at American Family Field. Here’s a San Diego Padres vs Milwaukee Brewers Prediction. This article will include a San Diego Padres vs Milwaukee Brewers Pick.

San Diego Padres Betting Preview

The San Diego Padres are 36-26 on the year and play the Dodgers, Diamondbacks, and Dodgers next. The San Diego Padres are batting .249 on the season, have a .314 OBP, and a .379 slugging percentage. The San Diego Padres pitching staff has a 3.50 ERA and a 1.20 WHIP. Manny Machado leads the San Diego Padres with 73 hits and 32 RBI, while Fernando Tatis Jr. and Luis Arraez have combined for 126 hits and 50 RBI. 

Stephen Kolek gets the ball for the San Diego Padres, and he is 3-1 with a 3.47 ERA and 27 strikeouts this season. Kolek is 1-0 with a 0.00 ERA and 2 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 34-30 on the year and play the Braves, Cardinals, and Cubs next. The Milwaukee Brewers are batting .237 on the season, have a .315 OBP, and a .365 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.88 ERA and a 1.32 WHIP. Jackson Chourio leads the Milwaukee Brewers with 71 hits and 37 RBI, while Sal Frelick and Brice Turang have combined for 126 hits and 46 RBI.

Jose Quintana gets the ball for the Milwaukee Brewers, and he is 4-1 with a 2.77 ERA and 27 strikeouts this season. Quintana is 3-0 with a 4.25 ERA and 31 strikeouts in his career against the San Diego Padres.

Why the Milwaukee Brewers will win

Why the San Diego Padres will win

Milwaukee Brewers Player Prop Facts

San Diego Padres Player Prop Facts

San Diego Padres vs Milwaukee Brewers Prediction

The Padres and the cheap price is appealing, but Kolek still has more to prove with just six career starts under his belt. The Brewers haven’t lost two straight games since May 24, and Quintana has found the fountain of youth at 36 years old. Through 39 innings, Quintana has allowed 35 hits and 12 earned runs. The Brewers have won five of Quintana’s seven games this season. Obviously we need to see a larger sample size before we can really crown Quintana, and he’s pitched just once over the last month. I’m still rolling with the Brewers at home in this near toss-up matchup.

Randy Chambers's Pick: Milwaukee Brewers -115

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