San Diego Padres vs Colorado Rockies Prediction 9/7/2025 Today’s MLB Picks

The San Diego Padres and the Colorado Rockies meet Sunday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Colorado Rockies Prediction.

Starting Pitching Matchup

The San Diego Padres will start Dylan Cease here and Cease is 6-11 with a 4.81 ERA and 190 strikeouts this season. In his last five starts against the Rockies, Cease is 2-2 with a 4.50 ERA and 35 strikeouts. Tanner Gordon will get the start for Colorado and is 5-5 with a 6.07 ERA and 41 strikeouts this season. This will be Gordon’s second career start against the Padres.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their 10-8 win over the Rockies from Saturday’s matchup to improve to 77-65 this season. After this series, the Padres will head home for a series against the Cincinnati Reds. 

Padres Snap Five-Game Losing Streak

Manny Machado has 153 hits including a team-high 32 doubles, 22 home runs, 81 RBIs and 12 stolen bases while Fernando Tatis Jr. has 136 hits with 19 home runs and 58 RBIs along with 27 stolen bases of his own this season. Luis Arraez has added 155 hits with 29 doubles, 4 triples, 7 home runs and 52 RBIs while Jackson Merrill’s added 91 hits with 9 home runs and 51 RBIs as well. Xander Bogaerts also has 29 doubles and 20 stolen bases as well this season. Gavin Sheets also has 23 doubles, 18 home runs and 62 RBIs as well this season.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to looking to bounce back from their loss at the hands of the Padres on Saturday to sit at 40-102 this season. After this series, the Rockies will head on the road for a division set against the Los Angeles Dodgers.

Rockies Drop Four Of Last Five

Hunter Goodman leads the Rockies with 129 hits including 24 doubles, 4 triples, 27 home runs and 83 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 126 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 14 home runs, 25 doubles, 46 RBIs, 5 triples and 15 stolen bases. Brenton Doyle has 107 hits with 19 doubles, 14 home runs, 54 RBIs and 15 stolen bases. Mickey Moniak has 96 hits with 17 doubles, 8 triples and 18 home runs with 55 RBIs. 

San Diego Padres @ Colorado Rockies Betting Trends: September 7, 2025

• Probable Starting Pitcher: Tanner Gordon      Record this season: 5-5      ERA: 6.07
• Home Record: 4-2
• Last 5 against Padres: 0-0

Why the Colorado Rockies will win

• The Padres have lost five of their last six games as road favorites against the Rockies following a win.
• The underdogs have won four of the Padres’ last five games.
• The Rockies have covered the run line in each of their last nine Sunday home games against NL West opponents.
• The Padres have failed to cover the run line in eight of their last nine games as favorites following a road win.
• The Padres have trailed after 3 innings in four of their last five road games against NL West opponents.
• The Padres have trailed after 5 innings in 10 of their last 11 road games.

• Probable Starting Pitcher: Dylan Cease      Record this season: 6-11      ERA: 4.81
• Road Record: 0-8
• Last 5 against Rockies: 2-2

Why the San Diego Padres will win

• The Rockies have lost 12 of their last 13 games after playing the previous day.
• The Padres have won five of their last six road games against NL West opponents that held a losing record.
• The Padres have covered the run line in eight of their last nine games against NL West opponents following a win.
• The Rockies have failed to cover the run line in each of their last four games after playing the previous day.
• The Rockies have lost the first inning in three of their last four day games against NL West opponents.
• The Rockies have trailed after 3 innings in five of their last six games against NL West opponents.
• The Padres have led after 5 innings in seven of their last eight games against NL West opponents.

Total Runs Facts

• Five of the Padres’ last six road games after playing the previous day have gone OVER the total runs line.
• Four of the last five games between the Padres and Rockies have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last six road games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the last seven day games between the Padres and Rockies at Coors Field.

Colorado Rockies Player Prop Facts

• Brenton Doyle has hit a home run in each of the Rockies’ last two day games against NL West opponents that held a winning record.
• Brenton Doyle has recorded at least one hit in 17 of his last 18 home appearances against opponents that held a winning record.
• German Marquez has recorded a Double in each of his last three home appearances against the Padres.

San Diego Padres Player Prop Facts

• Manny Machado has recorded a Double in each of the Padres’ last four day games against NL opponents that held a losing record.
• Fernando Tatis Jr. has hit a home run in two of the Padres’ last three games.
• Dylan Cease has recorded a win in each of his four previous appearances with the Padres as road favorites against NL West opponents.
• Dylan Cease has recorded seven or more strikeouts in eight of his last nine appearances with the Padres as favorites.
• Luis Campusano has recorded at least one hit in each of his last seven appearances with the Padres as road favorites against NL West opponents.
• Luis Arraez ranks 4th in the league in Hits (158) this season.

Matchup/League Facts

• The Rockies rank 1st in the league for triples this season (35).
• The Rockies rank 30th in the league for walks this season (353).
• The Padres rank 1st in the league for opponent batting average this season (.227).
• The Padres rank 1st in the league for hits allowed this season (1055).

San Diego Padres vs. Colorado Rockies Prediction

I’m on the over in this one. Dylan Cease has struggled to begin with on the road this season with a still-inflated ERA despite how late in the season we’re looking at here, and playing at Coors Field isn’t going to help matters here. On the other side, Tanner Gordon’s been hittable as well this season and in the end, I just think this is going to be a high-scoring game. Give me the over.