San Diego Padres vs Colorado Rockies Prediction 9/16/2026 Today’s MLB Picks
Chris Ruffolo
Sep 14, 2026; Denver, Colorado, USA; Colorado Rockies relief pitcher Juan Mejia (47) pitches in the seventh inning against the San Diego Padres at Coors Field. Mandatory Credit: Isaiah J. Downing-Imagn Images
MATCHUP
San Diego Padres
Colorado Rockies
Team Records
82-69
56-95
Spread
-1.5 -112
+1.5 -108
Moneyline
-172
+142
Total
Over 11 (-120)
Under 11 (100)
Where
Coors Field, Denver, Colorado
When
Wednesday, September 16, 2026
Time
08:40 PM EDT
TV
MLB.TV
The San Diego Padres and the Colorado Rockies meet Wednesday in MLB action from Coors Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Colorado Rockies prediction.
Starting Pitching Matchup
The San Diego Padres will send out Robbie Ray for the start here and Ray is 12-8 with a 3.57 ERA and 132 strikeouts this season. Colorado will start Mason Adams here and Adams is 0-0 with a 3.38 ERA and 22 strikeouts this season.
San Diego Padres Recap
The San Diego Padres come into this game looking to rebound from a 9-3 loss at the hands of the Colorado Rockies last time out to sit at 62-89 this season. After this series, the Padres will head home for a set against the Miami Marlins.
Padres Have 8-Game Win Streak Snapped
Entering Tuesday, Jackson Merrill has 143 hits with 25 doubles, 25 home runs and 83 RBIs while Gavin Sheets has 75 hits with 15 doubles, 16 home runs and 46 RBIs as well on the year. Fernando Tatis Jr. has 168 hits with 29 doubles, 22 home runs and 77 RBIs and Xander Bogaerts has 109 hits with 16 doubles, 11 home runs and 54 RBIs. Manny Machado also has 120 hits with 22 doubles, 28 home runs and 83 RBIs as well on the year.
Colorado Rockies Recap
The Colorado Rockies come into this game looking to add on to their win over the Padres from Tuesday to sit at 56-95 this season. After this series, the Rockies will take on the Seattle Mariners in a series at home.
Rockies Halt 8-Game Slide
Going into Tuesday, TJ Rumfield has 153 hits with 29 doubles, 3 triples, 15 home runs and 69 RBIs while Ezequiel Tovar has 93 hits with 21 doubles, 11 home runs and 42 RBIs. Hunter Goodman’s added 118 hits with 19 doubles, 38 home runs and 81 RBIs. Troy Johnston has 105 hits with 29 doubles, 4 home runs and 48 RBIs. Willi Castro also has 111 hits with 20 doubles, 15 home runs and 56 RBIs. Jake McCarthy also has 148 hits with 30 doubles, 10 triples, 15 home runs and 80 RBIs.
San Diego Padres @ Colorado Rockies Betting Trends: September 16, 2026
Probable Starting Pitcher: Mason Adams Record this season: 0-0 ERA: 3.38
Home Record: 0-0
Last 5 against Padres: –
Why the Colorado Rockies will win
The home team has won seven of the Rockies’ last eight games.
The Padres have lost each of their last four Wednesday games as road favorites.
The home team has covered the run line in each of the Rockies’ last eight games.
The Padres have failed to cover the run line in each of their last six Wednesday night games as road favorites against NL opponents.
The Padres have trailed after 5 innings in eight of their last nine Wednesday night road games.
Probable Starting Pitcher: Robbie Ray Record this season: 12-8 ERA: 3.57
Road Record: 6-5
Last 5 against Rockies: 1-0
Why the San Diego Padres will win
The Padres have won each of their last eight night games following a road loss.
The Rockies have lost each of their last seven games against the Padres following a win.
The Padres have covered the run line in each of their last nine games as favorites against NL West opponents following a loss.
The Rockies have failed to cover the run line in each of their last six games against the Padres following a win.
The Rockies have trailed after 3 innings in five of their last six night games against NL opponents.
The Rockies have trailed after 5 innings in each of their last 11 night games against opponents that held a winning record.
Total Runs Facts
Each of the Padres’ last seven games have gone OVER the total runs line.
Each of the Rockies’ last six night games against NL opponents have gone OVER the total runs line.
There has been at least one run scored in the first inning in each of the Padres’ last seven road games.
There has been at least one run scored in the first inning in each of the last four games between the Padres and Rockies at Coors Field.
Colorado Rockies Player Prop Facts
Cole Carrigg has hit at least one home run in each of the Rockies’ last two games.
Mason Adams has recorded five or more strikeouts in each of his four previous appearances.
TJ Rumfield has recorded at least one hit in each of his last 12 home appearances against NL West opponents.
TJ Rumfield ranks 4th amongst qualified players for On Base Percentage (.392) this season.
San Diego Padres Player Prop Facts
Fernando Tatis Jr. has hit a home run in three of the Padres’ last four games.
Robbie Ray has recorded five or more strikeouts in each of his last 11 Wednesday night appearances against teams that held a losing record.
Robbie Ray has recorded a win in each of his last six road appearances against NL opponents.
Austin Hays has recorded two hits in each of his last eight appearances with his team as a road favorite against NL West opponents.
Fernando Tatis Jr. ranks 4th in the league in Hits (169) this season.
Matchup/League Facts
The Rockies rank T1st in the league for doubles this season (271).
The Rockies rank 30th in the league for ERA this season (5.57).
The Padres rank T2nd in the league for steals this season (151).
The Padres rank 25th in the league for slugging percentage this season (.393).
San Diego Padres vs. Colorado Rockies Prediction
I’m on the Padres in this one. I just think the Padres are the better team in this one, and the Rockies outside of Tuesday’s win haven’t shown much in regards to their desire to play spoiler down the stretch. Mason Adams has been decent in his limited action, but I look for the Padres to bounce back here. Give me the Padres in this one.
