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San Diego Padres vs Arizona Diamondbacks Prediction 4/26/2026 Today’s MLB Picks

Apr 23, 2026; Denver, Colorado, USA; San Diego Padres first baseman Gavin Sheets (30) rounds the bases on a three run home run in the ninth inning against the Colorado Rockies at Coors Field. Mandatory Credit: Isaiah J. Downing-Imagn Images

Apr 23, 2026; Denver, Colorado, USA; San Diego Padres first baseman Gavin Sheets (30) rounds the bases on a three run home run in the ninth inning against the Colorado Rockies at Coors Field. Mandatory Credit: Isaiah J. Downing-Imagn Images

MATCHUP San Diego Padres Arizona Diamondbacks
Team Records 18-8 14-12
Where Chase Field, Phoenix, Arizona
When Sunday, April 26, 2026
Time 04:05 PM EDT
TV MLB.TV
The San Diego Padres and Arizona Diamondbacks meet Sunday in MLB action at Estadio Alfredo Harp Helú. Here’s a San Diego Padres vs. Arizona Diamondbacks Prediction. This article will include a San Diego Padres vs. Arizona Diamondbacks Pick.

San Diego Padres Betting Preview


The San Diego Padres are 18-8 on the year and play the Cubs and White Sox next. The San Diego Padres are batting. 233 on the season, have a .310 OBP, and have a .373 slugging percentage. The San Diego Padres pitching staff has a 3.63 ERA and a 1.25 WHIP. Xander Bogaerts leads the San Diego Padres with 26 hits and 16 RBI, while Ramon Laureano and Fernando Tatis Jr. have combined for 48 hits and 30 RBI.

Michael King gets the ball for the San Diego Padres, and he is 3-1 with a 2.28 ERA and 26 strikeouts this season. King is 2-0 with a 0.00 ERA and 11 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview


The Arizona Diamondbacks are 14-2 on the year and play the Cubs and Brewers next. The Arizona Diamondbacks are batting. 249 on the season, have a .304 OBP, and have a .413 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.44 ERA and a 1.32 WHIP. Ildemaro Vargas leads the Arizona Diamondbacks with 26 hits and 16 RBI while Nolan Arenado and Ketel Marte have combined for 48 hits and 23 RBI.

Ryne Nelson gets the ball for the Arizona Diamondbacks, and he is 1-2 with a 6.97 ERA and 20 strikeouts this season. Nelson is 4-3 with a 4.83 ERA and 40 strikeouts in his career against the San Diego Padres.

Why the Arizona Diamondbacks will win

Why the San Diego Padres will win

Total Runs Facts

Arizona Diamondbacks Player Prop Facts

San Diego Padres Player Prop Facts

San Diego Padres vs Arizona Diamondbacks Prediction


I’ve said it before in previous write-ups: this Padres team has some magic to them and I’m not looking to step in front of them. They’re rolling. King has also been solid despite his walk issue, as he has a 2.28 ERA and 1.12 WHIP. Nelson has a 6.97 ERA and 1.45 WHIP, and now he gets to pitch in the altitude of Mexico City. I’m sure he’s going to do just fine. I’ll gladly take the Padres and the cheap price.

Randy Chambers's Pick: San Diego Padres

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