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Reds vs Nationals Prediction 07/22/2025 Picks

Jun 24, 2025; Cincinnati, Ohio, USA; Cincinnati Reds starting pitcher Chase Burns (26) pitches against the New York Yankees in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Jun 24, 2025; Cincinnati, Ohio, USA; Cincinnati Reds starting pitcher Chase Burns (26) pitches against the New York Yankees in the first inning at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Cincinnati (52-49) vs Washington (40-60)

July 22, 2025 at 06:45 PM EDT

The Line: Betting Odds: Washington +1.5 — Over/Under: +8.5

(Get latest betting odds)

In this article, we will formulate a Reds vs Nationals prediction for this MLB game on Tuesday, July 22nd at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 52-49 this year after they dropped game one by a score of 10-8 on Monday night. Cincinnati cut the deficit from 7-0 to 7-5 in the fourth inning, but they allowed three more runs and came up short in the ninth. The Reds recorded nine hits in the game, and they were led by Marte and Lux, who both had two RBIs in the loss. Cincinnati started Singer, who allowed five hits and seven earned runs over 2.1 innings for the loss, while Richardson allowed three hits and one earned run in relief. 

Prior to this series, the Reds won two out of three against the Mets and two out of three against the Rockies. Cincinnati has won four of its last six games and they are currently fourth in the NL Central standings. The Cincinnati pitching staff has a 3.94 ERA with a 1.25 WHIP and a .237 opponent batting average, while their offense has scored 464 runs with a .246 batting average and a .319 on-base percentage this season. Elly De La Cruz has led Cincinnati with 18 home runs and 65 RBIs, while Spencer Steer has added 11 home runs and 41 RBIs this year. The projected starting pitcher for Cincinnati is Chase Burns, who is 0-1 with a 6.19 ERA and a 1.63 WHIP over 16.0 innings pitched this year. 

Washington Nationals Betting Preview

The Washington Nationals are 40-60 this season after they won game one to start this series on Monday. Washington jumped out to a 7-0 lead, but their bullpen nearly blew the game in the ninth. The Nationals recorded 15 hits in the game, and they were led by Lile, who went 2-4 with three RBIs in the win. Washington started Irvin, who allowed six hits and five earned runs over 3.2 innings, while Finnegan allowed two hits and two earned runs in the ninth. 

Prior to this series, the Nationals lost two out of three against the Padres and all three against the Brewers. Washington has lost six of their last eight games, and they are currently last in the NL East standings. The Washington pitching staff has a 5.25 ERA with a 1.41 WHIP and a .264 opponent batting average, while the offense has scored 434 runs with a .246 batting average and a .312 on-base percentage this season. James Wood has led Washington with 24 home runs and 70 RBIs, while Nathaniel Lowe has added 15 home runs and 62 RBIs this year. The projected starting pitcher for Washington is Brad Lord, who is 2-5 with a 3.46 ERA and a 1.25 WHIP over 65.0 innings pitched this season. 

Why the Reds will beat the Nationals

The Nationals have lost 11 of their last 12 games following a win.
The Nationals have failed to cover the run line in each of their last four night games against NL Central opponents following a win.
The Reds have covered the run line in four of their last five games.

Total Runs Facts

Nine of the Nationals’ last 10 games as home underdogs have gone OVER the total runs line.
Six of the Reds’ last seven games after playing the previous day have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Reds’ last six games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the last 14 night games between the Reds and Nationals.

Washington Nationals Player Prop Facts

Josh Bell has hit a home run in three of his last four appearances against the Reds.
Amed Rosario has recorded a Double in three of his last four home appearances against former teams.
Amed Rosario has recorded at least one hit in each of his last eight home appearances against opponents that held a winning record.

Cincinnati Reds Player Prop Facts

Jake Fraley has recorded a Double in each of his last three appearances at Nationals Park against opponents that held a losing record.
Spencer Steer has recorded at least one hit in each of the Reds’ last nine games as road favorites against NL opponents.
Elly De La Cruz has hit a home run in six of the Reds’ last 20 road games.

Reds vs Nationals Prediction 

Washington has had a very rough season so far, but they picked up a nice win on Monday and will look to make it two in a row here. The Nationals are 20-30 at home this year, while the Reds are 24-27 on the road. Cincinnati has lost two games in a row, and they are starting Burns, who has allowed three earned runs and six hits in his last 10.2 innings. Washington is going with Lord, who will operate as an opener. I know the Nats got the win on Monday, but I don’t trust this pitching staff at all, and I don’t see them winning two straight. Take the Reds here. 

David Racey's Pick: Reds ML

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